VIM-2

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

Epitope information of EP0019

Epitope IDEP0019
Epitope nameVIM-2
Structure
SequenceNeu5Ac(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-)-R
AliasesCD65, CDw65, Sialyl Lewis i-X
HistoryA mouse monoclonal antibody,VIM-2,specific for human blood cells of myelomonocytic lineage,was found to bind to a series of minor gangliosides isolated from the cells of patients with chronic myelogenous leukemia(1985).[3][1*]
DB JCGGDB
Molecular weight1348.2
Composition(Fuc)1(Gal)3(GlcNAc)2(Neu5Ac)1
Species

Homo sapiens

Tissue and Cellular distribution

myeloid cell

Subcellular distribution

Developmental change

Cell line

HL-60/human promyelocytic leukemia

Receptor

Function

CDw65 have been shown to interact with the ELAM-1 molecule on activated endothelium.[2][4]

Diseases

Application
Comment