FH2 / FH-2

Antibody IDAN0261
Epitope ID EP0011
Epitope nameLewis x
Recognition regionGal(b1-4)[Fuc(a1-3)]GlcNAc(b1-)-R
Immunoprecipitation
Immunoblot[5*][6]
ELISA/RIA[1][3*][6]
Flow cytometry
Histochemistry[1][2][4]
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgM
Immunogen
Availability
Applications
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1 Izawa M, Kumamoto K, Mitsuoka C, Kanamori C, Kanamori A, Ohmori K, Ishida H, Nakamura S, Kurata-Miura K, Sasaki K, Nishi T, Kannagi R.
Expression of sialyl 6-sulfo Lewis X is inversely correlated with conventional sialyl Lewis X expression in human colorectal cancer.
Cancer Res. 2000 Mar 1;60(5):1410-6
PMID: 10728707
2 Ohtani H, Fukushi Y, Orikasa S, Nagura H.
Qualitative difference of subcellular localization of tumor-associated carbohydrate (Le(x)) antigens in renal cell carcinoma and normal kidney.
J Histochem Cytochem. 1991 Apr ;39(4):479-84
PMID: 1672317
3 Fukushi Y, Hakomori S, Nudelman E, Cochran N.
Novel fucolipids accumulating in human adenocarcinoma. II. Selective isolation of hybridoma antibodies that differentially recognize mono-, di-, and trifucosylated type 2 chain.
J Biol Chem. 1984 Apr 10;259(7):4681-5
PMID: 6200484
4 Nakayama J, Ota H, Katsuyama T, Kanai M, Taki T, Hirabayashi Y, Suzuki Y.
Immunohistochemical demonstration of glycoconjugates bearing the type 2 chain-backbone structure in human fetal, normal and neoplastic gastrointestinal tract.
Histochemistry. 1992 May ;97(4):303-10
PMID: 1618643
5 Hirabayashi Y, Fujita SC, Kon K, Ando S.
Characterization of a novel Le(x)-active ganglioside from chick intestinal tissues recognized by murine monoclonal antibody 188C1.
J Biol Chem. 1991 Jun 5;266(16):10268-74
PMID: 1674743
6 Okada Y, Arima T, Nagashima H, Fukushi Y, Kannagi R, Kaizu T.
Human hepatocellular carcinoma-associated changes of glycosphingolipids detected by two monoclonal antibodies FH2 and IB9.
J Hepatol. 1986 ;2(3):430-40
PMID: 2424969