10E4
| Antibody ID | AN0148 |
|---|
| Epitope ID | EP0086 |
|---|---|
| Epitope name | Heparan Sulfate |
| Recognition region | -[GlcA(b1-4)GlcNSO3(a1-4)]n- (GlcA-GlcNS) -[GlcA(b1-4)GlcNAc(a1-4)]n- (GlcA-GlcNAc) |
| Immunoprecipitation | |
| Immunoblot | [1][2] |
| ELISA/RIA | [7*][5][3*] |
| Flow cytometry | [7*] |
| Histochemistry | [7*][1][2][4][5][6][8][3*] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | heparan sulfate proteoglycans from human fetal lung fibroblasts[1] |
| Availability | SEIKAGAKU BIOBUSINESS CORPORATION -English SEIKAGAKU BIOBUSINESS CORPORATION -Japanese |
| Applications |
| 1 | David G, Bai XM, Van der Schueren B, Cassiman JJ, Van den Berghe H. Developmental changes in heparan sulfate expression: in situ detection with mAbs. J Cell Biol. 1992 Nov ;119(4):961-75 PMID: 1385449 |
|---|---|
| 2 | Bai XM, Van der Schueren B, Cassiman JJ, Van den Berghe H, David G. Differential expression of multiple cell-surface heparan sulfate proteoglycans during embryonic tooth development. J Histochem Cytochem. 1994 Aug ;42(8):1043-54 PMID: 8027524 |
| 3 | van Kuppevelt TH, Dennissen MA, van Venrooij WJ, Hoet RM, Veerkamp JH. Generation and application of type-specific anti-heparan sulfate antibodies using phage display technology. Further evidence for heparan sulfate heterogeneity in the kidney. J Biol Chem. 1998 May 22;273(21):12960-6 PMID: 9582329 |
| 4 | Fuxe K, Chadi G, Tinner B, Agnati LF, Pettersson R, David G. On the regional distribution of heparan sulfate proteoglycan immunoreactivity in the rat brain. Brain Res. 1994 Feb 4;636(1):131-8 PMID: 7512431 |
| 5 | Yokoyama H, Sato K, Okudaira M, Morita C, Takahashi C, Suzuki D, Sakai H, Iwamoto Y. Serum and urinary concentrations of heparan sulfate in patients with diabetic nephropathy. Kidney Int. 1999 Aug ;56(2):650-8 PMID: 10432405 |
| 6 | Oshiro M, Ono K, Suzuki Y, Ota H, Katsuyama T, Mori N. Immunohistochemical localization of heparan sulfate proteoglycan in human gastrointestinal tract. Histochem Cell Biol. 2001 May ;115(5):373-80 PMID: 11449885 |
| 7 | van den Born J, Salmivirta K, Henttinen T, Ostman N, Ishimaru T, Miyaura S, Yoshida K, Salmivirta M. Novel heparan sulfate structures revealed by monoclonal antibodies. J Biol Chem. 2005 May 27;280(21):20516-23 PMID: 15778504 |
| 8 | Cheng F, Mani K, van den Born J, Ding K, Belting M, Fransson LA. Nitric oxide-dependent processing of heparan sulfate in recycling S-nitrosylated glypican-1 takes place in caveolin-1-containing endosomes. J Biol Chem. 2002 Nov 15;277(46):44431-9 PMID: 12226079 |