AM-3
| Antibody ID | AN0018 |
|---|
| Epitope ID | EP0012 |
|---|---|
| Epitope name | Sialyl Lewis x |
| Recognition region | Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R |
| Immunoprecipitation | |
| Immunoblot | [1] |
| ELISA/RIA | |
| Flow cytometry | |
| Histochemistry | [2][3] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | |
| Availability | |
| Applications |
| 1 | Hanski C, Hanski ML, Zimmer T, Ogorek D, Devine P, Riecken EO. Characterization of the major sialyl-Lex-positive mucins present in colon, colon carcinoma, and sera of patients with colorectal cancer. Cancer Res. 1995 Feb 15;55(4):928-33 PMID: 7850810 |
|---|---|
| 2 | Grabowski P, Mann B, Mansmann U, Lovin N, Foss HD, Berger G, Scherubl H, Riecken EO, Buhr HJ, Hanski C. Expression of SIALYL-Le(x) antigen defined by MAb AM-3 is an independent prognostic marker in colorectal carcinoma patients. Int J Cancer. 2000 Oct 15;88(2):281-6 PMID: 11004681 |
| 3 | Wagers AJ, Stoolman LM, Kannagi R, Craig R, Kansas GS. Expression of leukocyte fucosyltransferases regulates binding to E-selectin: relationship to previously implicated carbohydrate epitopes. J Immunol. 1997 Aug 15;159(4):1917-29 PMID: 9257857 |