CSLEX1 / CSLEX-1
| Antibody ID | AN0262 |
|---|
| Epitope ID | EP0012 |
|---|---|
| Epitope name | Sialyl Lewis x |
| Recognition region | Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R Neu5Ac(a2-3)[HSO3(-6)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R |
| Immunoprecipitation | [1] |
| Immunoblot | [2][5] |
| ELISA/RIA | [5] |
| Flow cytometry | |
| Histochemistry | [3][4] |
| Comment |
| Epitope ID | EP0014 |
|---|---|
| Epitope name | 6'-Sulfo Sialyl Lewis x |
| Recognition region | Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R Neu5Ac(a2-3)[HSO3(-6)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R |
| Immunoprecipitation | [1] |
| Immunoblot | [2] |
| ELISA/RIA | |
| Flow cytometry | |
| Histochemistry | [3][4] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | |
| Availability | BD Biosciences |
| Applications |
| 1 | Cai S, Davis AE 3rd. Complement regulatory protein C1 inhibitor binds to selectins and interferes with endothelial-leukocyte adhesion. J Immunol. 2003 Nov 1;171(9):4786-91 PMID: 14568956 |
|---|---|
| 2 | Nakagoe T, Fukushima K, Sawai T, Tsuji T, Jibiki M, Nanashima A, Tanaka K, Yamaguchi H, Yasutake T, Ayabe H, Ishikawa H. Increased expression of sialyl Lewis(x) antigen in penetrating growth type A early gastric cancer. J Exp Clin Cancer Res. 2002 Sep ;21(3):363-9 PMID: 12385579 |
| 3 | Zhang K, Chuluyan HE, Hardie D, Shen DC, Larsen R, Issekutz A. Novel monoclonal antibodies to putative selectin carbohydrate ligands that inhibit selectin binding to myeloid cells. Hybridoma. 1998 Oct ;17(5):445-56 PMID: 9873990 |
| 4 | Wagers AJ, Stoolman LM, Kannagi R, Craig R, Kansas GS. Expression of leukocyte fucosyltransferases regulates binding to E-selectin: relationship to previously implicated carbohydrate epitopes. J Immunol. 1997 Aug 15;159(4):1917-29 PMID: 9257857 |
| 5 | Fukushima K, Hirota M, Terasaki PI, Wakisaka A, Togashi H, Chia D, Suyama N, Fukushi Y, Nudelman E, Hakomori S. Characterization of sialosylated Lewisx as a new tumor-associated antigen. Cancer Res. 1984 Nov ;44(11):5279-85 PMID: 6386148 |