2F3

Antibody IDAN0006
Epitope ID EP0012
Epitope nameSialyl Lewis x
Recognition regionNeu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R
Neu5Ac(a2-3)[HSO3(-6)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R
Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)][HSO3(-6)]GlcNAc(b1-3)Gal(b1-)-R
Neu5Ac(a2-3)[HSO3(-6)]Gal(b1-4)[Fuc(a1-3)][HSO3(-6)]GlcNAc(b1-3)Gal(b1-)-R
Immunoprecipitation
Immunoblot[3]
ELISA/RIA
Flow cytometry
Histochemistry[1][2]
Comment
Epitope ID EP0014
Epitope name6'-Sulfo Sialyl Lewis x
Recognition regionNeu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R
Neu5Ac(a2-3)[HSO3(-6)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R
Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)][HSO3(-6)]GlcNAc(b1-3)Gal(b1-)-R
Neu5Ac(a2-3)[HSO3(-6)]Gal(b1-4)[Fuc(a1-3)][HSO3(-6)]GlcNAc(b1-3)Gal(b1-)-R
Immunoprecipitation
Immunoblot
ELISA/RIA
Flow cytometry
Histochemistry[1][2]
Comment
Epitope ID EP0015
Epitope nameSialyl 6-Sulfo Lewis x
Recognition regionNeu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R
Neu5Ac(a2-3)[HSO3(-6)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R
Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)][HSO3(-6)]GlcNAc(b1-3)Gal(b1-)-R
Neu5Ac(a2-3)[HSO3(-6)]Gal(b1-4)[Fuc(a1-3)][HSO3(-6)]GlcNAc(b1-3)Gal(b1-)-R
Immunoprecipitation
Immunoblot
ELISA/RIA
Flow cytometry
Histochemistry[1][2]
Comment
Epitope ID EP0016
Epitope name6,6'- Disulfo Sialyl Lewis x
Recognition regionNeu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R
Neu5Ac(a2-3)[HSO3(-6)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-)-R
Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)][HSO3(-6)]GlcNAc(b1-3)Gal(b1-)-R
Neu5Ac(a2-3)[HSO3(-6)]Gal(b1-4)[Fuc(a1-3)][HSO3(-6)]GlcNAc(b1-3)Gal(b1-)-R
Immunoprecipitation
Immunoblot
ELISA/RIA
Flow cytometry
Histochemistry[1]
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgM
Immunogensialyl Lewis x glycolipid´╝łIV3Neu5AcIII3FucnLc4Cer)[3]
Availability
Applications
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1 Renkonen J, Tynninen O, Hayry P, Paavonen T, Renkonen R.
Glycosylation might provide endothelial zip codes for organ-specific leukocyte traffic into inflammatory sites.
Am J Pathol. 2002 Aug ;161(2):543-50
PMID: 12163379
2 Wagers AJ, Stoolman LM, Kannagi R, Craig R, Kansas GS.
Expression of leukocyte fucosyltransferases regulates binding to E-selectin: relationship to previously implicated carbohydrate epitopes.
J Immunol. 1997 Aug 15;159(4):1917-29
PMID: 9257857
3 Ohmori K, Takada A, Ohwaki I, Takahashi N, Furukawa Y, Maeda M, Kiso M, Hasegawa A, Kannagi M, Kannagi R.
A distinct type of sialyl Lewis X antigen defined by a novel monoclonal antibody is selectively expressed on helper memory T cells.
Blood. 1993 Nov 1;82(9):2797-805
PMID: 7693048