RL2 / RL-2

Antibody IDAN0385
Epitope ID EP0004
Epitope nameO-GlcNAc
Recognition regionGlcNAc(b1-)Ser/Thr
Flow cytometry
Affinity BioReagents
Santa Cruz Biotechnology, Inc.
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1 Holt GD, Snow CM, Senior A, Haltiwanger RS, Gerace L, Hart GW.
Nuclear pore complex glycoproteins contain cytoplasmically disposed O-linked N-acetylglucosamine.
J Cell Biol. 1987 May ;104(5):1157-64
PMID: 3571327
2 Snow CM, Senior A, Gerace L.
Monoclonal antibodies identify a group of nuclear pore complex glycoproteins.
J Cell Biol. 1987 May ;104(5):1143-56
PMID: 2437126
3 Walgren JL, Vincent TS, Schey KL, Buse MG.
High glucose and insulin promote O-GlcNAc modification of proteins, including alpha-tubulin.
Am J Physiol Endocrinol Metab. 2003 Feb ;284(2):E424-34
PMID: 12397027
4 Guinez C, Lemoine J, Michalski JC, Lefebvre T.
70-kDa-heat shock protein presents an adjustable lectinic activity towards O-linked N-acetylglucosamine.
Biochem Biophys Res Commun. 2004 Jun 18;319(1):21-6
PMID: 15158436
5 Lefebvre T, Pinte S, Guerardel C, Deltour S, Martin-Soudant N, Slomianny MC, Michalski JC, Leprince D.
The tumor suppressor HIC1 (hypermethylated in cancer 1) is O-GlcNAc glycosylated.
Eur J Biochem. 2004 Oct ;271(19):3843-54
PMID: 15373830
6 Buse MG, Robinson KA, Marshall BA, Hresko RC, Mueckler MM.
Enhanced O-GlcNAc protein modification is associated with insulin resistance in GLUT1-overexpressing muscles.
Am J Physiol Endocrinol Metab. 2002 Aug ;283(2):E241-50
PMID: 12110528
7 Gao Y, Miyazaki J, Hart GW.
The transcription factor PDX-1 is post-translationally modified by O-linked N-acetylglucosamine and this modification is correlated with its DNA binding activity and insulin secretion in min6 beta-cells.
Arch Biochem Biophys. 2003 Jul 15;415(2):155-63
PMID: 12831837
8 Zraika S, Dunlop M, Proietto J, Andrikopoulos S.
The hexosamine biosynthesis pathway regulates insulin secretion via protein glycosylation in mouse islets.
Arch Biochem Biophys. 2002 Sep 15;405(2):275-9
PMID: 12220542
9 Andrali SS, Marz P, Ozcan S.
Ataxin-10 interacts with O-GlcNAc transferase OGT in pancreatic beta cells.
Biochem Biophys Res Commun. 2005 Nov 11;337(1):149-53
PMID: 16182253
10 Sohn KC, Lee KY, Park JE, Do SI.
OGT functions as a catalytic chaperone under heat stress response: a unique defense role of OGT in hyperthermia.
Biochem Biophys Res Commun. 2004 Sep 24;322(3):1045-51
PMID: 15336570
11 Cauet G, Strub JM, Leize E, Wagner E, Van Dorsselaer A, Lusky M.
Identification of the glycosylation site of the adenovirus type 5 fiber protein.
Biochemistry. 2005 Apr 12;44(14):5453-60
PMID: 15807538
12 Cheng X, Cole RN, Zaia J, Hart GW.
Alternative O-glycosylation/O-phosphorylation of the murine estrogen receptor beta.
Biochemistry. 2000 Sep 26;39(38):11609-20
PMID: 10995228
13 Gewinner C, Hart G, Zachara N, Cole R, Beisenherz-Huss C, Groner B.
The coactivator of transcription CREB-binding protein interacts preferentially with the glycosylated form of Stat5.
J Biol Chem. 2004 Jan 30;279(5):3563-72
PMID: 14597631
14 Meyer BH, Luus HG, Muller FO, Badenhorst PN, Lotter MG, Rothig HJ, Grotsch H, Rosenkranz B.
Recombinant hirudin, a new anticoagulant, has no effect on faecal blood loss.
Br J Clin Pharmacol. 1992 May ;33(5):524-6
PMID: 1524967
15 Cieniewski-Bernard C, Bastide B, Lefebvre T, Lemoine J, Mounier Y, Michalski JC.
Identification of O-linked N-acetylglucosamine proteins in rat skeletal muscle using two-dimensional gel electrophoresis and mass spectrometry.
Mol Cell Proteomics. 2004 Jun ;3(6):577-85
PMID: 14985449
16 Hanover JA, Lai Z, Lee G, Lubas WA, Sato SM.
Elevated O-linked N-acetylglucosamine metabolism in pancreatic beta-cells.
Arch Biochem Biophys. 1999 Feb 1;362(1):38-45
PMID: 9917327
17 Du XL, Edelstein D, Rossetti L, Fantus IG, Goldberg H, Ziyadeh F, Wu J, Brownlee M.
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation.
Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12222-6
PMID: 11050244