HH8
Antibody ID | AN0035 |
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Epitope ID | EP0020 |
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Epitope name | T Antigen |
Recognition region | Gal(b1-3)GalNAc(a1-)Ser/Thr |
Immunoprecipitation | |
Immunoblot | [1] |
ELISA/RIA | [2] |
Flow cytometry | [3][5] |
Histochemistry | [4][5] |
Comment |
Species | Mouse |
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Category | Monoclonal |
Isotype | IgM |
Immunogen | |
Availability | |
Applications |
1 | Langkilde NC, Wolf H, Clausen H, Orntoft TF. Human urinary bladder carcinoma glycoconjugates expressing T-(Gal beta(1-3)GalNAc alpha 1-O-R) and T-like antigens: a comparative study using peanut agglutinin and poly- and monoclonal antibodies. Cancer Res. 1992 Sep 15;52(18):5030-6 PMID: 1516058 |
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2 | Kjeldsen T, Clausen H, Hirohashi S, Ogawa T, Iijima H, Hakomori S. Preparation and characterization of monoclonal antibodies directed to the tumor-associated O-linked sialosyl-2----6 alpha-N-acetylgalactosaminyl (sialosyl-Tn) epitope. Cancer Res. 1988 Apr 15;48(8):2214-20 PMID: 2450649 |
3 | Pinho S, Marcos NT, Ferreira B, Carvalho AS, Oliveira MJ, Santos-Silva F, Harduin-Lepers A, Reis CA. Biological significance of cancer-associated sialyl-Tn antigen: Modulation of malignant phenotype in gastric carcinoma cells. Cancer Lett. 2006 Sep 9;[Epub ahead of print]: PMID: 16965854 |
4 | Rajpert-De Meyts E, Poll SN, Goukasian I, Jeanneau C, Herlihy AS, Bennett EP, Skakkebaek NE, Clausen H, Giwercman A, Mandel U. Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation. Virchows Arch. 2007 Oct ;451(4):805-14 PMID: 17694322 |
5 | Marcos NT, Pinho S, Grandela C, Cruz A, Samyn-Petit B, Harduin-Lepers A, Almeida R, Silva F, Morais V, Costa J, Kihlberg J, Clausen H, Reis CA. Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen. Cancer Res. 2004 Oct 1;64(19):7050-7 PMID: 15466199 |