HH8

Antibody IDAN0035
Epitope ID EP0020
Epitope nameT Antigen
Recognition regionGal(b1-3)GalNAc(a1-)Ser/Thr
Immunoprecipitation
Immunoblot[1]
ELISA/RIA[2]
Flow cytometry[3][5]
Histochemistry[4][5]
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgM
Immunogen
Availability
Applications
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1 Langkilde NC, Wolf H, Clausen H, Orntoft TF.
Human urinary bladder carcinoma glycoconjugates expressing T-(Gal beta(1-3)GalNAc alpha 1-O-R) and T-like antigens: a comparative study using peanut agglutinin and poly- and monoclonal antibodies.
Cancer Res. 1992 Sep 15;52(18):5030-6
PMID: 1516058
2 Kjeldsen T, Clausen H, Hirohashi S, Ogawa T, Iijima H, Hakomori S.
Preparation and characterization of monoclonal antibodies directed to the tumor-associated O-linked sialosyl-2----6 alpha-N-acetylgalactosaminyl (sialosyl-Tn) epitope.
Cancer Res. 1988 Apr 15;48(8):2214-20
PMID: 2450649
3 Pinho S, Marcos NT, Ferreira B, Carvalho AS, Oliveira MJ, Santos-Silva F, Harduin-Lepers A, Reis CA.
Biological significance of cancer-associated sialyl-Tn antigen: Modulation of malignant phenotype in gastric carcinoma cells.
Cancer Lett. 2006 Sep 9;[Epub ahead of print]:
PMID: 16965854
4 Rajpert-De Meyts E, Poll SN, Goukasian I, Jeanneau C, Herlihy AS, Bennett EP, Skakkebaek NE, Clausen H, Giwercman A, Mandel U.
Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation.
Virchows Arch. 2007 Oct ;451(4):805-14
PMID: 17694322
5 Marcos NT, Pinho S, Grandela C, Cruz A, Samyn-Petit B, Harduin-Lepers A, Almeida R, Silva F, Morais V, Costa J, Kihlberg J, Clausen H, Reis CA.
Role of the human ST6GalNAc-I and ST6GalNAc-II in the synthesis of the cancer-associated sialyl-Tn antigen.
Cancer Res. 2004 Oct 1;64(19):7050-7
PMID: 15466199