CC49
| Antibody ID | AN0086 |
|---|
| Epitope ID | EP0022 |
|---|---|
| Epitope name | Sialyl Tn Antigen |
| Recognition region | Neu5Ac(a2-6)GalNAc(a1-)Ser/Thr |
| Immunoprecipitation | [3] |
| Immunoblot | [1] |
| ELISA/RIA | |
| Flow cytometry | [2] |
| Histochemistry | |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgG1 |
| Immunogen | MAbＢ72.3 reactive tumor-associated glycoprotein (TAG) -72, isolated from human colon cancer cells[1] |
| Availability | abcam |
| Applications |
| 1 | Muraro R, Kuroki M, Wunderlich D, Poole DJ, Colcher D, Thor A, Greiner JW, Simpson JF, Molinolo A, Noguchi P, et al. Generation and characterization of B72.3 second generation monoclonal antibodies reactive with the tumor-associated glycoprotein 72 antigen. Cancer Res. 1988 Aug 15;48(16):4588-96 PMID: 3396010 |
|---|---|
| 2 | Ragupathi G, Liu NX, Musselli C, Powell S, Lloyd K, Livingston PO. Antibodies against tumor cell glycolipids and proteins, but not mucins, mediate complement-dependent cytotoxicity. J Immunol. 2005 May 1;174(9):5706-12 PMID: 15843572 |
| 3 | Kuroki M, Fernsten PD, Wunderlich D, Colcher D, Simpson JF, Poole DJ, Schlom J. Serological mapping of the TAG-72 tumor-associated antigen using 19 distinct monoclonal antibodies. Cancer Res. 1990 Aug 15;50(16):4872-9 PMID: 1696162 |