CC49

Antibody IDAN0086
Epitope ID EP0022
Epitope nameSialyl Tn Antigen
Recognition regionNeu5Ac(a2-6)GalNAc(a1-)Ser/Thr
Immunoprecipitation[3]
Immunoblot[1]
ELISA/RIA
Flow cytometry[2]
Histochemistry
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgG1
ImmunogenMAb´╝ó72.3 reactive tumor-associated glycoprotein (TAG) -72, isolated from human colon cancer cells[1]
Availabilityabcam
Applications
Up  Down
1 Muraro R, Kuroki M, Wunderlich D, Poole DJ, Colcher D, Thor A, Greiner JW, Simpson JF, Molinolo A, Noguchi P, et al.
Generation and characterization of B72.3 second generation monoclonal antibodies reactive with the tumor-associated glycoprotein 72 antigen.
Cancer Res. 1988 Aug 15;48(16):4588-96
PMID: 3396010
2 Ragupathi G, Liu NX, Musselli C, Powell S, Lloyd K, Livingston PO.
Antibodies against tumor cell glycolipids and proteins, but not mucins, mediate complement-dependent cytotoxicity.
J Immunol. 2005 May 1;174(9):5706-12
PMID: 15843572
3 Kuroki M, Fernsten PD, Wunderlich D, Colcher D, Simpson JF, Poole DJ, Schlom J.
Serological mapping of the TAG-72 tumor-associated antigen using 19 distinct monoclonal antibodies.
Cancer Res. 1990 Aug 15;50(16):4872-9
PMID: 1696162