MLS132 (MLS102)
| Antibody ID | AN0089 |
|---|
| Epitope ID | EP0022 |
|---|---|
| Epitope name | Sialyl Tn Antigen |
| Recognition region | Neu5Ac(a2-6)GalNAc(a1-)Ser/Thr |
| Immunoprecipitation | [2] |
| Immunoblot | [1] |
| ELISA/RIA | [4] |
| Flow cytometry | |
| Histochemistry | [2][3] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgG3 |
| Immunogen | LS180/human colon adenocarcinoma[2] |
| Availability | Wako Pure Chemical Industries, Ltd. |
| Applications |
| 1 | Nakada H, Inoue M, Tanaka N, Yamashina I. Coexpression of cancer-associated carbohydrate antigens, Tn and sialyl Tn. Glycoconj J. 1994 Jun ;11(3):262-5 PMID: 7841802 |
|---|---|
| 2 | Fukui S, Numata Y, Kurosaka A, Kitagawa H, Nakada H, Funakoshi I, Kawasaki T, Takahashi Y, Hayashi K, Yamashina I. Production of monoclonal antibodies directed against carbohydrate moieties of cell surface glycoproteins. Jpn J Cancer Res. 1988 Oct ;79(10):1119-29 PMID: 3143700 |
| 3 | Ching CK, Holmes SW, Holmes GK, Long RG. Blood-group sialyl-Tn antigen is more specific than Tn as a tumor marker in the pancreas. Pancreas. 1994 Nov ;9(6):698-702 PMID: 7846011 |
| 4 | Kjeldsen T, Clausen H, Hirohashi S, Ogawa T, Iijima H, Hakomori S. Preparation and characterization of monoclonal antibodies directed to the tumor-associated O-linked sialosyl-2----6 alpha-N-acetylgalactosaminyl (sialosyl-Tn) epitope. Cancer Res. 1988 Apr 15;48(8):2214-20 PMID: 2450649 |