DUPAN-2

Antibody IDAN0101
Epitope ID EP0041
Epitope nameSialyl Lewis c
Recognition regionNeu5Ac(a2-3)Gal(b1-3)GlcNAc(b1-)-R
Neu5Ac(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-)-R
Immunoprecipitation[6]
Immunoblot[5][2][6]
ELISA/RIA
Flow cytometry
Histochemistry[1][3][4]
Comment
Species-
CategoryMonoclonal
IsotypeIgM
Immunogen
Availability
Applications
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1 Chiaravalli AM, Cornaggia M, Furlan D, Capella C, Fiocca R, Tagliabue G, Klersy C, Solcia E.
The role of histological investigation in prognostic evaluation of advanced gastric cancer. Analysis of histological structure and molecular changes compared with invasive pattern and stage.
Virchows Arch. 2001 Aug ;439(2):158-69
PMID: 11561756
2 Kawa S, Kato M, Oguchi H, Kobayashi T, Furuta S, Kanai M.
Preparation of pancreatic cancer-associated mucin expressing CA19-9, CA50, Span-1, sialyl SSEA-1, and Dupan-2.
Scand J Gastroenterol. 1991 Sep ;26(9):981-92
PMID: 1682994
3 Tajiri T, Tate G, Kunimura T, Inoue K, Mitsuya T, Yoshiba M, Morohosh T.
Histologic and immunohistochemical comparison of intraductal tubular carcinoma, intraductal papillary-mucinous carcinoma, and ductal adenocarcinoma of the pancreas.
Pancreas. 2004 Aug ;29(2):116-22
PMID: 15257103
4 Hayashi N, Nakamori S, Okami J, Nagano H, Dono K, Umeshita K, Sakon M, Narimatsu H, Monden M.
Association between expression levels of CA 19-9 and N-acetylglucosamine-beta;1,3-galactosyltransferase 5 gene in human pancreatic cancer tissue.
Pathobiology. 2004 ;71(1):26-34
PMID: 14555842
5 Hamanaka Y, Hamanaka S, Shinagawa Y, Suzuki T, Inagaki F, Suzuki M, Suzuki A.
Ganglioside antigen of DU-PAN-2 in a human pancreatic cancer.
FEBS Lett. 1994 Oct 10;353(1):48-52
PMID: 7926020
6 Lan MS, Finn OJ, Fernsten PD, Metzgar RS.
Isolation and properties of a human pancreatic adenocarcinoma-associated antigen, DU-PAN-2.
Cancer Res. 1985 Jan ;45(1):305-10
PMID: 3965141