EM1

Antibody IDAN0701
Epitope ID EP0059
Epitope nameGD1b
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot
ELISA/RIA[3][4][1]
Flow cytometry
Histochemistry
CommentReacted to sulfatide.[1]
Epitope ID EP0062
Epitope nameN-Acetyl GD3
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot[2]
ELISA/RIA[2][3][4][1]
Flow cytometry
Histochemistry
CommentReacted to sulfatide.[1]
Epitope ID EP0066
Epitope nameGT1a
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot[2]
ELISA/RIA[2][4]
Flow cytometry
Histochemistry
CommentReacted to sulfatide.[1]
Epitope ID EP0067
Epitope nameGT1b
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot
ELISA/RIA[3][1]
Flow cytometry
Histochemistry
CommentReacted to sulfatide.[1]
Epitope ID EP0069
Epitope nameGQ1b
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot[2]
ELISA/RIA[2][3][4][1]
Flow cytometry
Histochemistry
CommentReacted to sulfatide.[1]
Epitope ID EP0308
Epitope nameNeu5Ac(a2-8)Neu5Ac(a2-3)Gal
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot[2]
ELISA/RIA[2][3][4][1]
Flow cytometry
Histochemistry
CommentReacted to sulfatide.[1]
SpeciesMouse
CategoryMonoclonal
IsotypeIgM(k)
Immunogen
Availability
Applications
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1 Townson K, Greenshields KN, Veitch J, Nicholl D, Eckhardt M, Galanina O, Bovin N, Samain E, Antoine T, Bundle D, Zhang P, Ling CC, Willison HJ.
Sulfatide binding properties of murine and human antiganglioside antibodies.
Glycobiology. 2007 Nov ;17(11):1156-66
PMID: 17855742
2 Goodyear CS, O'Hanlon GM, Plomp JJ, Wagner ER, Morrison I, Veitch J, Cochrane L, Bullens RW, Molenaar PC, Conner J, Willison HJ.
Monoclonal antibodies raised against Guillain-Barré syndrome-associated Campylobacter jejuni lipopolysaccharides react with neuronal gangliosides and paralyze muscle-nerve preparations.
J Clin Invest. 1999 Sep ;104(6):697-708
PMID: 10491405
3 Willison HJ, Townson K, Veitch J, Boffey J, Isaacs N, Andersen SM, Zhang P, Ling CC, Bundle DR.
Synthetic disialylgalactose immunoadsorbents deplete anti-GQ1b antibodies from autoimmune neuropathy sera.
Brain. 2004 Mar ;127(Pt 3):680-91
PMID: 14960498
4 Boffey J, Nicholl D, Wagner ER, Townson K, Goodyear C, Furukawa K, Furukawa K, Conner J, Willison HJ.
Innate murine B cells produce anti-disialosyl antibodies reactive with Campylobacter jejuni LPS and gangliosides that are polyreactive and encoded by a restricted set of unmutated V genes.
J Neuroimmunol. 2004 Jul ;152(1-2):98-111
PMID: 15223242