EM1
Antibody ID | AN0701 |
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Epitope ID | EP0059 |
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Epitope name | GD1b |
Recognition region | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal-R |
Immunoprecipitation | |
Immunoblot | |
ELISA/RIA | [3][4][1] |
Flow cytometry | |
Histochemistry | |
Comment | Reacted to sulfatide.[1] |
Epitope ID | EP0062 |
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Epitope name | N-Acetyl GD3 |
Recognition region | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal-R |
Immunoprecipitation | |
Immunoblot | [2] |
ELISA/RIA | [2][3][4][1] |
Flow cytometry | |
Histochemistry | |
Comment | Reacted to sulfatide.[1] |
Epitope ID | EP0066 |
---|---|
Epitope name | GT1a |
Recognition region | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal-R |
Immunoprecipitation | |
Immunoblot | [2] |
ELISA/RIA | [2][4] |
Flow cytometry | |
Histochemistry | |
Comment | Reacted to sulfatide.[1] |
Epitope ID | EP0067 |
---|---|
Epitope name | GT1b |
Recognition region | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal-R |
Immunoprecipitation | |
Immunoblot | |
ELISA/RIA | [3][1] |
Flow cytometry | |
Histochemistry | |
Comment | Reacted to sulfatide.[1] |
Epitope ID | EP0069 |
---|---|
Epitope name | GQ1b |
Recognition region | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal-R |
Immunoprecipitation | |
Immunoblot | [2] |
ELISA/RIA | [2][3][4][1] |
Flow cytometry | |
Histochemistry | |
Comment | Reacted to sulfatide.[1] |
Epitope ID | EP0308 |
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Epitope name | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal |
Recognition region | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal-R |
Immunoprecipitation | |
Immunoblot | [2] |
ELISA/RIA | [2][3][4][1] |
Flow cytometry | |
Histochemistry | |
Comment | Reacted to sulfatide.[1] |
Species | Mouse |
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Category | Monoclonal |
Isotype | IgM(k) |
Immunogen | |
Availability | |
Applications |
1 | Townson K, Greenshields KN, Veitch J, Nicholl D, Eckhardt M, Galanina O, Bovin N, Samain E, Antoine T, Bundle D, Zhang P, Ling CC, Willison HJ. Sulfatide binding properties of murine and human antiganglioside antibodies. Glycobiology. 2007 Nov ;17(11):1156-66 PMID: 17855742 |
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2 | Goodyear CS, O'Hanlon GM, Plomp JJ, Wagner ER, Morrison I, Veitch J, Cochrane L, Bullens RW, Molenaar PC, Conner J, Willison HJ. Monoclonal antibodies raised against Guillain-Barré syndrome-associated Campylobacter jejuni lipopolysaccharides react with neuronal gangliosides and paralyze muscle-nerve preparations. J Clin Invest. 1999 Sep ;104(6):697-708 PMID: 10491405 |
3 | Willison HJ, Townson K, Veitch J, Boffey J, Isaacs N, Andersen SM, Zhang P, Ling CC, Bundle DR. Synthetic disialylgalactose immunoadsorbents deplete anti-GQ1b antibodies from autoimmune neuropathy sera. Brain. 2004 Mar ;127(Pt 3):680-91 PMID: 14960498 |
4 | Boffey J, Nicholl D, Wagner ER, Townson K, Goodyear C, Furukawa K, Furukawa K, Conner J, Willison HJ. Innate murine B cells produce anti-disialosyl antibodies reactive with Campylobacter jejuni LPS and gangliosides that are polyreactive and encoded by a restricted set of unmutated V genes. J Neuroimmunol. 2004 Jul ;152(1-2):98-111 PMID: 15223242 |