126
| Antibody ID | AN0580 |
|---|
| Epitope ID | EP0061 |
|---|---|
| Epitope name | GD2 |
| Recognition region | GalNAc(b1-4)[Neu5Ac(a2-8)Neu5Ac(a2-3)]Gal(b1-4)Glc(b1-1)Cer |
| Immunoprecipitation | |
| Immunoblot | [2][1][3] |
| ELISA/RIA | [2][1][3][4] |
| Flow cytometry | [4] |
| Histochemistry | |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | LAN-1/human neuroblastoma[2] |
| Availability | ATCC |
| Applications |
| 1 | Cheresh DA, Harper JR, Schulz G, Reisfeld RA. Localization of the gangliosides GD2 and GD3 in adhesion plaques and on the surface of human melanoma cells. Proc Natl Acad Sci U S A. 1984 Sep ;81(18):5767-71 PMID: 6385004 |
|---|---|
| 2 | Schulz G, Cheresh DA, Varki NM, Yu A, Staffileno LK, Reisfeld RA. Detection of ganglioside GD2 in tumor tissues and sera of neuroblastoma patients. Cancer Res. 1984 Dec ;44(12 Pt 1):5914-20 PMID: 6498849 |
| 3 | Cheresh DA, Rosenberg J, Mujoo K, Hirschowitz L, Reisfeld RA. Biosynthesis and expression of the disialoganglioside GD2, a relevant target antigen on small cell lung carcinoma for monoclonal antibody-mediated cytolysis. Cancer Res. 1986 Oct ;46(10):5112-8 PMID: 3019521 |
| 4 | Cheresh DA, Pierschbacher MD, Herzig MA, Mujoo K. Disialogangliosides GD2 and GD3 are involved in the attachment of human melanoma and neuroblastoma cells to extracellular matrix proteins. J Cell Biol. 1986 Mar ;102(3):688-96 PMID: 3005335 |