CGM4

Antibody IDAN0694
Epitope ID EP0062
Epitope nameN-Acetyl GD3
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot[1]
ELISA/RIA[1][2][3]
Flow cytometry
Histochemistry
CommentNot reacted to GD1b and GT1b.[2][3]
Gal in the recognition region should not have branched structure.[2][3][4]
Epitope ID EP0066
Epitope nameGT1a
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot[1]
ELISA/RIA[1][3]
Flow cytometry
Histochemistry
CommentNot reacted to GD1b and GT1b.[2][3]
Gal in the recognition region should not have branched structure.[2][3][4]
Epitope ID EP0069
Epitope nameGQ1b
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot[1]
ELISA/RIA[1][2][3]
Flow cytometry
Histochemistry
CommentNot reacted to GD1b and GT1b.[2][3]
Gal in the recognition region should not have branched structure.[2][3][4]
Epitope ID EP0308
Epitope nameNeu5Ac(a2-8)Neu5Ac(a2-3)Gal
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot[1]
ELISA/RIA[1][2][3]
Flow cytometry
Histochemistry
CommentNot reacted to GD1b and GT1b.[2][3]
Gal in the recognition region should not have branched structure.[2][3][4]
SpeciesMouse
CategoryMonoclonal
IsotypeIgM(k)
Immunogen
Availability
Applications
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1 Goodyear CS, O'Hanlon GM, Plomp JJ, Wagner ER, Morrison I, Veitch J, Cochrane L, Bullens RW, Molenaar PC, Conner J, Willison HJ.
Monoclonal antibodies raised against Guillain-Barré syndrome-associated Campylobacter jejuni lipopolysaccharides react with neuronal gangliosides and paralyze muscle-nerve preparations.
J Clin Invest. 1999 Sep ;104(6):697-708
PMID: 10491405
2 Willison HJ, Townson K, Veitch J, Boffey J, Isaacs N, Andersen SM, Zhang P, Ling CC, Bundle DR.
Synthetic disialylgalactose immunoadsorbents deplete anti-GQ1b antibodies from autoimmune neuropathy sera.
Brain. 2004 Mar ;127(Pt 3):680-91
PMID: 14960498
3 Boffey J, Nicholl D, Wagner ER, Townson K, Goodyear C, Furukawa K, Furukawa K, Conner J, Willison HJ.
Innate murine B cells produce anti-disialosyl antibodies reactive with Campylobacter jejuni LPS and gangliosides that are polyreactive and encoded by a restricted set of unmutated V genes.
J Neuroimmunol. 2004 Jul ;152(1-2):98-111
PMID: 15223242
4 Boffey J, Odaka M, Nicoll D, Wagner ER, Townson K, Bowes T, Conner J, Furukawa K, Willison HJ.
Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire.
J Neuroimmunol. 2005 Aug ;165(1-2):92-103
PMID: 15967512