S2-566

Antibody IDAN0128
Epitope ID EP0062
Epitope nameN-Acetyl GD3
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot
ELISA/RIA
Flow cytometry
Histochemistry
Comment
Epitope ID EP0067
Epitope nameGT1b
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot
ELISA/RIA
Flow cytometry
Histochemistry
Comment
Epitope ID EP0069
Epitope nameGQ1b
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot
ELISA/RIA
Flow cytometry
Histochemistry
Comment
Epitope ID EP0101
Epitope namePoly-N-Acetylneuraminic Acid
Recognition regionNeu5Ac(a2-8)Neu5Ac(a2-3)Gal-R
Immunoprecipitation
Immunoblot[1*]
ELISA/RIA[1*]
Flow cytometry
Histochemistry
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgM
ImmunogenSK-MEL-28/human melanoma[2]
AvailabilitySEIKAGAKU BIOBUSINESS CORPORATION -English
SEIKAGAKU BIOBUSINESS CORPORATION -Japanese
Applications
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1 Sato C, Fukuoka H, Ohta K, Matsuda T, Koshino R, Kobayashi K, Troy FA 2nd, Kitajima K.
Frequent occurrence of pre-existing alpha 2-->8-linked disialic and oligosialic acids with chain lengths up to 7 Sia residues in mammalian brain glycoproteins. Prevalence revealed by highly sensitive chemical methods and anti-di-, oligo-, and poly-Sia antibodies specific for defined chain lengths.
J Biol Chem. 2000 May 19;275(20):15422-31
PMID: 10809778
2 Miyazaki H, Shiku H, Furukawa K.
Differential effects of a murine monoclonal antibody reactive with the disialylgalactosyl residue on the growth of melanoma cells and T cell activation.
Int J Oncol. 1996 Aug ;9(2):241-5
PMID: 21541506