CGM4
| Antibody ID | AN0694 |
|---|
| Epitope ID | EP0062 |
|---|---|
| Epitope name | N-Acetyl GD3 |
| Recognition region | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal-R |
| Immunoprecipitation | |
| Immunoblot | [1] |
| ELISA/RIA | [1][2][3] |
| Flow cytometry | |
| Histochemistry | |
| Comment | Not reacted to GD1b and GT1b.[2][3] Gal in the recognition region should not have branched structure.[2][3][4] |
| Epitope ID | EP0066 |
|---|---|
| Epitope name | GT1a |
| Recognition region | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal-R |
| Immunoprecipitation | |
| Immunoblot | [1] |
| ELISA/RIA | [1][3] |
| Flow cytometry | |
| Histochemistry | |
| Comment | Not reacted to GD1b and GT1b.[2][3] Gal in the recognition region should not have branched structure.[2][3][4] |
| Epitope ID | EP0069 |
|---|---|
| Epitope name | GQ1b |
| Recognition region | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal-R |
| Immunoprecipitation | |
| Immunoblot | [1] |
| ELISA/RIA | [1][2][3] |
| Flow cytometry | |
| Histochemistry | |
| Comment | Not reacted to GD1b and GT1b.[2][3] Gal in the recognition region should not have branched structure.[2][3][4] |
| Epitope ID | EP0308 |
|---|---|
| Epitope name | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal |
| Recognition region | Neu5Ac(a2-8)Neu5Ac(a2-3)Gal-R |
| Immunoprecipitation | |
| Immunoblot | [1] |
| ELISA/RIA | [1][2][3] |
| Flow cytometry | |
| Histochemistry | |
| Comment | Not reacted to GD1b and GT1b.[2][3] Gal in the recognition region should not have branched structure.[2][3][4] |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM(k) |
| Immunogen | |
| Availability | |
| Applications |
| 1 | Goodyear CS, O'Hanlon GM, Plomp JJ, Wagner ER, Morrison I, Veitch J, Cochrane L, Bullens RW, Molenaar PC, Conner J, Willison HJ. Monoclonal antibodies raised against Guillain-Barré syndrome-associated Campylobacter jejuni lipopolysaccharides react with neuronal gangliosides and paralyze muscle-nerve preparations. J Clin Invest. 1999 Sep ;104(6):697-708 PMID: 10491405 |
|---|---|
| 2 | Willison HJ, Townson K, Veitch J, Boffey J, Isaacs N, Andersen SM, Zhang P, Ling CC, Bundle DR. Synthetic disialylgalactose immunoadsorbents deplete anti-GQ1b antibodies from autoimmune neuropathy sera. Brain. 2004 Mar ;127(Pt 3):680-91 PMID: 14960498 |
| 3 | Boffey J, Nicholl D, Wagner ER, Townson K, Goodyear C, Furukawa K, Furukawa K, Conner J, Willison HJ. Innate murine B cells produce anti-disialosyl antibodies reactive with Campylobacter jejuni LPS and gangliosides that are polyreactive and encoded by a restricted set of unmutated V genes. J Neuroimmunol. 2004 Jul ;152(1-2):98-111 PMID: 15223242 |
| 4 | Boffey J, Odaka M, Nicoll D, Wagner ER, Townson K, Bowes T, Conner J, Furukawa K, Willison HJ. Characterisation of the immunoglobulin variable region gene usage encoding the murine anti-ganglioside antibody repertoire. J Neuroimmunol. 2005 Aug ;165(1-2):92-103 PMID: 15967512 |