MSW113

Antibody IDAN0450
Epitope ID EP0008
Epitope nameSialyl Lewis a
Recognition regionNeu5Ac(a2-3)Gal(b1-3)GlcNAc(b1-)-R
Neu5Ac(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-)-R
Immunoprecipitation
Immunoblot[1*]
ELISA/RIA[2*][3][4]
Flow cytometry
Histochemistry
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgG3(k)
ImmunogenSW1116/human colon adenocarcinoma[4]
AvailabilityWako Pure Chemical Industries, Ltd.
Applications
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1 Kitagawa H, Nakada H, Fukui S, Funakoshi I, Kawasaki T, Tate S, Inagaki F, Yamashina I.
Novel gangliosides containing the sialyl-Le(a) structure from a human rectal adenocarcinoma.
J Biol Chem. 1993 Dec 15;268(35):26541-5
PMID: 8253783
2 Kitagawa H, Nakada H, Numata Y, Kurosaka A, Fukui S, Funakoshi I, Kawasaki T, Shimada I, Inagaki F, Yamashina I.
Occurrence of tetra- and pentasaccharides with the sialyl-Le(a) structure in human milk.
J Biol Chem. 1990 Mar 25;265(9):4859-62
PMID: 2318868
3 Kannagi R, Takada A, Shigeta K, Itai S, Hashimoto K.
[2D3 series, MSW 113 and other monoclonal antibodies directed to type 1 chain carbohydrate antigens]
Nippon Rinsho. 1990 Feb ;48 Suppl:992-8
PMID: 2355641
4 Kitagawa H, Nakada H, Numata Y, Kurosaka A, Fukui S, Funakoshi I, Kawasaki T, Yamashina I.
A monoclonal antibody that recognizes sialyl-Lea oligosaccharide, but is distinct from NS 19-9 as to epitope recognition.
J Biochem. 1988 Nov ;104(5):817-21
PMID: 2466827