38.13
| Antibody ID | AN0212 |
|---|
| Epitope ID | EP0045 |
|---|---|
| Epitope name | Pk Antigen |
| Recognition region | Gal(a1-4)Gal(b1-4)Glc-R |
| Immunoprecipitation | |
| Immunoblot | [1][2*] |
| ELISA/RIA | |
| Flow cytometry | [3*] |
| Histochemistry | [2*] |
| Comment |
| Epitope ID | EP0071 |
|---|---|
| Epitope name | Gb3 |
| Recognition region | Gal(a1-4)Gal(b1-4)Glc-R |
| Immunoprecipitation | |
| Immunoblot | [1][2*] |
| ELISA/RIA | |
| Flow cytometry | [3*] |
| Histochemistry | [2*] |
| Comment |
| Species | Rat |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | |
| Availability | Beckman Coulter Santa Cruz Biotechnology, Inc. AbD Serotec abcam |
| Applications |
| 1 | Cooling LL, Walker KE, Gille T, Koerner TA. Shiga toxin binds human platelets via globotriaosylceramide (Pk antigen) and a novel platelet glycosphingolipid. Infect Immun. 1998 Sep ;66(9):4355-66 PMID: 9712788 |
|---|---|
| 2 | Okuda T, Tokuda N, Numata S, Ito M, Ohta M, Kawamura K, Wiels J, Urano T, Tajima O, Furukawa K, Furukawa K. Targeted disruption of Gb3/CD77 synthase gene resulted in the complete deletion of globo-series glycosphingolipids and loss of sensitivity to verotoxins. J Biol Chem. 2006 Apr 14;281(15):10230-5 PMID: 16476743 |
| 3 | Kojima Y, Fukumoto S, Furukawa K, Okajima T, Wiels J, Yokoyama K, Suzuki Y, Urano T, Ohta M, Furukawa K. Molecular cloning of globotriaosylceramide/CD77 synthase, a glycosyltransferase that initiates the synthesis of globo series glycosphingolipids. J Biol Chem. 2000 May 19;275(20):15152-6 PMID: 10748143 |