2H6G5

Antibody IDAN0134
Epitope ID EP0080
Epitope nameSD1a
Recognition regionHSO3(-3)Gal(b1-3)GalNAc(b1-4)[HSO3(-3)]Gal(b1-4)Glc(b1-1)Cer
Immunoprecipitation
Immunoblot[3][2]
ELISA/RIA[3][1]
Flow cytometry[3]
Histochemistry
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgM
Immunogenacidic glycolipid mixture prepared from human hepatocellular carcinoma cells (PLC/PRF/5)[3]
AvailabilitySEIKAGAKU BIOBUSINESS CORPORATION -English
SEIKAGAKU BIOBUSINESS CORPORATION -Japanese
Applications
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1 Hiraiwa N, Fukuda Y, Imura H, Tadano-Aritomi K, Nagai K, Ishizuka I, Kannagi R.
Accumulation of highly acidic sulfated glycosphingolipids in human hepatocellular carcinoma defined by a series of monoclonal antibodies.
Cancer Res. 1990 May 15;50(10):2917-28
PMID: 2159366
2 Suzuki Y, Toda Y, Tamatani T, Watanabe T, Suzuki T, Nakao T, Murase K, Kiso M, Hasegawa A, Tadano-Aritomi K.
Sulfated glycolipids are ligands for a lymphocyte homing receptor, L-selectin (LECAM-1), Binding epitope in sulfated sugar chain.
Biochem Biophys Res Commun. 1993 Jan 29;190(2):426-34
PMID: 7678958
3 Hiraiwa N, Iida N, Ishizuka I, Itai S, Shigeta K, Kannagi R, Fukuda Y, Imura H.
Monoclonal antibodies directed to a disulfated glycosphingolipid, SB1a (GgOse4Cer-II3IV3-bis-sulfate), associated with human hepatocellular carcinoma.
Cancer Res. 1988 Dec 1;48(23):6769-74
PMID: 2846160