HS4C3
| Antibody ID | AN0332 |
|---|
| Epitope ID | EP0086 |
|---|---|
| Epitope name | Heparan Sulfate |
| Recognition region | -{[HSO3(-6)]GlcNSO3(a1-4)[HSO3(-2)]IdoA(a1-4)}- (GlcNS6S-IdoA2S) -{[HSO3(-6)][HSO3(-3)]GlcNSO3(a1-4)[HSO3(-2)]IdoA(a1-4)}- (GlcNS6S3S-IdoA2S) 3-O-sulfated HS stractures |
| Immunoprecipitation | [3*] |
| Immunoblot | |
| ELISA/RIA | [2*][3*] |
| Flow cytometry | |
| Histochemistry | [2*][1][3*] |
| Comment |
| Species | Human |
|---|---|
| Category | Single chain Fv |
| Isotype | - |
| Immunogen | |
| Availability | |
| Applications |
| 1 | ten Dam GB, Hafmans T, Veerkamp JH, van Kuppevelt TH. Differential expression of heparan sulfate domains in rat spleen. J Histochem Cytochem. 2003 Jun ;51(6):727-39 PMID: 12754284 |
|---|---|
| 2 | van Kuppevelt TH, Dennissen MA, van Venrooij WJ, Hoet RM, Veerkamp JH. Generation and application of type-specific anti-heparan sulfate antibodies using phage display technology. Further evidence for heparan sulfate heterogeneity in the kidney. J Biol Chem. 1998 May 22;273(21):12960-6 PMID: 9582329 |
| 3 | Ten Dam GB, Kurup S, van de Westerlo EM, Versteeg EM, Lindahl U, Spillmann D, van Kuppevelt TH. 3-O-sulfated oligosaccharide structures are recognized by anti-heparan sulfate antibody HS4C3. J Biol Chem. 2006 Feb 24;281(8):4654-62 PMID: 16373349 |