J403 / J-403
| Antibody ID | AN0452 |
|---|
| Epitope ID | EP0086 |
|---|---|
| Epitope name | Heparan Sulfate |
| Recognition region | -[GlcA(b1-4)GlcN(a1-4)]n- (GIcA-GlcN) |
| Immunoprecipitation | |
| Immunoblot | |
| ELISA/RIA | [3*][2*][7][1][8] |
| Flow cytometry | [3*] |
| Histochemistry | [3*][4][2*][5][6][7][1*][8][9][10] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | |
| Availability | SEIKAGAKU BIOBUSINESS CORPORATION -English SEIKAGAKU BIOBUSINESS CORPORATION -Japanese |
| Applications |
| 1 | van den Born J, Gunnarsson K, Bakker MA, Kjellen L, Kusche-Gullberg M, Maccarana M, Berden JH, Lindahl U. Presence of N-unsubstituted glucosamine units in native heparan sulfate revealed by a monoclonal antibody. J Biol Chem. 1995 Dec 29;270(52):31303-9 PMID: 8537400 |
|---|---|
| 2 | van Kuppevelt TH, Dennissen MA, van Venrooij WJ, Hoet RM, Veerkamp JH. Generation and application of type-specific anti-heparan sulfate antibodies using phage display technology. Further evidence for heparan sulfate heterogeneity in the kidney. J Biol Chem. 1998 May 22;273(21):12960-6 PMID: 9582329 |
| 3 | van den Born J, Salmivirta K, Henttinen T, Ostman N, Ishimaru T, Miyaura S, Yoshida K, Salmivirta M. Novel heparan sulfate structures revealed by monoclonal antibodies. J Biol Chem. 2005 May 27;280(21):20516-23 PMID: 15778504 |
| 4 | Cheng F, Mani K, van den Born J, Ding K, Belting M, Fransson LA. Nitric oxide-dependent processing of heparan sulfate in recycling S-nitrosylated glypican-1 takes place in caveolin-1-containing endosomes. J Biol Chem. 2002 Nov 15;277(46):44431-9 PMID: 12226079 |
| 5 | van den Born J, van den Heuvel LP, Bakker MA, Veerkamp JH, Assmann KJ, Berden JH. A monoclonal antibody against GBM heparan sulfate induces an acute selective proteinuria in rats. Kidney Int. 1992 Jan ;41(1):115-23 PMID: 1593846 |
| 6 | Tamsma JT, van den Born J, Bruijn JA, Assmann KJ, Weening JJ, Berden JH, Wieslander J, Schrama E, Hermans J, Veerkamp JH, et al. Expression of glomerular extracellular matrix components in human diabetic nephropathy: decrease of heparan sulphate in the glomerular basement membrane. Diabetologia. 1994 Mar ;37(3):313-20 PMID: 8174847 |
| 7 | van den Born J, van den Heuvel LP, Bakker MA, Veerkamp JH, Assmann KJ, Berden JH. Monoclonal antibodies against the protein core and glycosaminoglycan side chain of glomerular basement membrane heparan sulfate proteoglycan: characterization and immunohistological application in human tissues. J Histochem Cytochem. 1994 Jan ;42(1):89-102 PMID: 8263327 |
| 8 | van Det NF, van den Born J, Tamsma JT, Verhagen NA, van den Heuvel LP, Berden JH, Bruijn JA, Daha MR, van der Woude FJ. Proteoglycan production by human glomerular visceral epithelial cells and mesangial cells in vitro. Biochem J. 1995 May 1;307 ( Pt 3):759-68 PMID: 7537959 |
| 9 | van der Pijl JW, Daha MR, van den Born J, Verhagen NA, Lemkes HH, Bucala R, Berden JH, Zwinderman AH, Bruijn JA, van Es LA, van der Woude FJ. Extracellular matrix in human diabetic nephropathy: reduced expression of heparan sulphate in skin basement membrane. Diabetologia. 1998 Jul ;41(7):791-8 PMID: 9686920 |
| 10 | Yard BA, Kahlert S, Engelleiter R, Resch S, Waldherr R, Groffen AJ, van den Heuvel LP, van der Born J, Berden JH, Kroger S, Hafner M, van der Woude FJ. Decreased glomerular expression of agrin in diabetic nephropathy and podocytes, cultured in high glucose medium. Exp Nephrol. 2001 ;9(3):214-22 PMID: 11340306 |