43-9F
| Antibody ID | AN0229 |
|---|
| Epitope ID | EP0091 |
|---|---|
| Epitope name | Lewis a- Lewis x Hybrid Antigen |
| Recognition region | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-)-R |
| Immunoprecipitation | |
| Immunoblot | [1][2] |
| ELISA/RIA | |
| Flow cytometry | |
| Histochemistry | [3] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgG |
| Immunogen | SLC-L11/human squamous lung carcinoma[1] |
| Availability | |
| Applications |
| 1 | Martensson S, Due C, Pahlsson P, Nilsson B, Eriksson H, Zopf D, Olsson L, Lundblad A. A carbohydrate epitope associated with human squamous lung cancer. Cancer Res. 1988 Apr 15;48(8):2125-31 PMID: 2450645 |
|---|---|
| 2 | Stroud MR, Levery SB, Martensson S, Salyan ME, Clausen H, Hakomori S. Human tumor-associated Le(a)-Le(x) hybrid carbohydrate antigen IV3(Gal beta 1-->3[Fuc alpha 1-->4]GlcNAc)III3FucnLc4 defined by monoclonal antibody 43-9F: enzymatic synthesis, structural characterization, and comparative reactivity with various antibodies. Biochemistry. 1994 Sep 6;33(35):10672-80 PMID: 7521211 |
| 3 | Pettijohn DE, Pfenninger O, Brown J, Duke R, Olsson L. Tumorigenic human squamous lung cancer cells have defined cell surface carbohydrates that are absent from nontumorigenic cells. Proc Natl Acad Sci U S A. 1988 Feb ;85(3):802-6 PMID: 3422461 |