NCC-ST-421
| Antibody ID | AN0228 |
|---|
| Epitope ID | EP0090 |
|---|---|
| Epitope name | Dimeric Lewis a |
| Recognition region | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-)-R Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-)-R |
| Immunoprecipitation | |
| Immunoblot | [2*] |
| ELISA/RIA | |
| Flow cytometry | |
| Histochemistry | [1] |
| Comment |
| Epitope ID | EP0091 |
|---|---|
| Epitope name | Lewis a- Lewis x Hybrid Antigen |
| Recognition region | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-)-R Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-)-R |
| Immunoprecipitation | |
| Immunoblot | [2*] |
| ELISA/RIA | |
| Flow cytometry | |
| Histochemistry | [1] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgG3 |
| Immunogen | |
| Availability | |
| Applications |
| 1 | Watanabe M, Ohishi T, Kuzuoka M, Nudelman ED, Stroud MR, Kubota T, Kodairo S, Abe O, Hirohashi S, Shimosato Y, et al. In vitro and in vivo antitumor effects of murine monoclonal antibody NCC-ST-421 reacting with dimeric Le(a) (Le(a)/Le(a)) epitope. Cancer Res. 1991 Apr 15;51(8):2199-204 PMID: 1706961 |
|---|---|
| 2 | Stroud MR, Levery SB, Nudelman ED, Salyan ME, Towell JA, Roberts CE, Watanabe M, Hakomori S. Extended type 1 chain glycosphingolipids: dimeric Lea (III4V4Fuc2Lc6) as human tumor-associated antigen. J Biol Chem. 1991 May 5;266(13):8439-46 PMID: 2022659 |