2-2B
| Antibody ID | AN0200 |
|---|
| Epitope ID | EP0101 |
|---|---|
| Epitope name | Poly-N-Acetylneuraminic Acid |
| Recognition region | (Neu5Ac)n n>4 |
| Immunoprecipitation | |
| Immunoblot | [1] |
| ELISA/RIA | [5*] |
| Flow cytometry | |
| Histochemistry | [1][2][3][4] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | viable Meningococcus group B(strain P355)[2] |
| Availability | Millipore |
| Applications |
| 1 | Beecken WD, Engl T, Ogbomo H, Relja B, Cinatl J, Bereiter-Hahn J, Oppermann E, Jonas D, Blaheta RA. Valproic acid modulates NCAM polysialylation and polysialyltransferase mRNA expression in human tumor cells. Int Immunopharmacol. 2005 Apr ;5(4):757-69 PMID: 15710344 |
|---|---|
| 2 | Rougon G, Dubois C, Buckley N, Magnani JL, Zollinger W. A monoclonal antibody against meningococcus group B polysaccharides distinguishes embryonic from adult N-CAM. J Cell Biol. 1986 Dec ;103(6 Pt 1):2429-37 PMID: 3536966 |
| 3 | Theodosis DT, Rougon G, Poulain DA. Retention of embryonic features by an adult neuronal system capable of plasticity: polysialylated neural cell adhesion molecule in the hypothalamo-neurohypophysial system. Proc Natl Acad Sci U S A. 1991 Jul 1;88(13):5494-8 PMID: 2062831 |
| 4 | Theodosis DT, Bonhomme R, Vitiello S, Rougon G, Poulain DA. Cell surface expression of polysialic acid on NCAM is a prerequisite for activity-dependent morphological neuronal and glial plasticity. J Neurosci. 1999 Dec 1;19(23):10228-36 PMID: 10575020 |
| 5 | Sato C, Fukuoka H, Ohta K, Matsuda T, Koshino R, Kobayashi K, Troy FA 2nd, Kitajima K. Frequent occurrence of pre-existing alpha 2-->8-linked disialic and oligosialic acids with chain lengths up to 7 Sia residues in mammalian brain glycoproteins. Prevalence revealed by highly sensitive chemical methods and anti-di-, oligo-, and poly-Sia antibodies specific for defined chain lengths. J Biol Chem. 2000 May 19;275(20):15422-31 PMID: 10809778 |