OL28

Antibody IDAN0191
Epitope ID EP0101
Epitope namePoly-N-Acetylneuraminic Acid
Recognition region(Neu5Ac)n n>4
Immunoprecipitation
Immunoblot[2*][1*]
ELISA/RIA[1*]
Flow cytometry
Histochemistry[3*]
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgM
Immunogenrat oligodendrocytes[4]
Availability
Applications
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1 Sato C, Fukuoka H, Ohta K, Matsuda T, Koshino R, Kobayashi K, Troy FA 2nd, Kitajima K.
Frequent occurrence of pre-existing alpha 2-->8-linked disialic and oligosialic acids with chain lengths up to 7 Sia residues in mammalian brain glycoproteins. Prevalence revealed by highly sensitive chemical methods and anti-di-, oligo-, and poly-Sia antibodies specific for defined chain lengths.
J Biol Chem. 2000 May 19;275(20):15422-31
PMID: 10809778
2 Close BE, Mendiratta SS, Geiger KM, Broom LJ, Ho LL, Colley KJ.
The minimal structural domains required for neural cell adhesion molecule polysialylation by PST/ST8Sia IV and STX/ST8Sia II.
J Biol Chem. 2003 Aug 15;278(33):30796-805
PMID: 12791681
3 Close BE, Colley KJ.
In vivo autopolysialylation and localization of the polysialyltransferases PST and STX.
J Biol Chem. 1998 Dec 18;273(51):34586-93
PMID: 9852130
4 Martersteck CM, Kedersha NL, Drapp DA, Tsui TG, Colley KJ.
Unique alpha 2, 8-polysialylated glycoproteins in breast cancer and leukemia cells.
Glycobiology. 1996 Apr ;6(3):289-301
PMID: 8724137