G72
| Antibody ID | AN0029 |
|---|
| Epitope ID | EP0015 |
|---|---|
| Epitope name | Sialyl 6-Sulfo Lewis x |
| Recognition region | Neu5Ac(a2-3)Gal(b1-4)[HSO3(-6)]GlcNAc(b1-)-R Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)][HSO3(-6)]GlcNAc(b1-)-R |
| Immunoprecipitation | |
| Immunoblot | [1*] |
| ELISA/RIA | [2] |
| Flow cytometry | |
| Histochemistry | [1*] |
| Comment |
| Epitope ID | EP0143 |
|---|---|
| Epitope name | Sialyl 6-Sulfo LacNAc |
| Recognition region | Neu5Ac(a2-3)Gal(b1-4)[Fuc(a1-3)][HSO3(-6)]GlcNAc(b1-)-R Neu5Ac(a2-3)Gal(b1-4)[HSO3(-6)]GlcNAc(b1-)-R |
| Immunoprecipitation | |
| Immunoblot | |
| ELISA/RIA | |
| Flow cytometry | [3*][4] |
| Histochemistry | |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | |
| Availability | |
| Applications |
| 1 | Mitsuoka C, Sawada-Kasugai M, Ando-Furui K, Izawa M, Nakanishi H, Nakamura S, Ishida H, Kiso M, Kannagi R. Identification of a major carbohydrate capping group of the L-selectin ligand on high endothelial venules in human lymph nodes as 6-sulfo sialyl Lewis X. J Biol Chem. 1998 May 1;273(18):11225-33 PMID: 9556613 |
|---|---|
| 2 | Izawa M, Kumamoto K, Mitsuoka C, Kanamori C, Kanamori A, Ohmori K, Ishida H, Nakamura S, Kurata-Miura K, Sasaki K, Nishi T, Kannagi R. Expression of sialyl 6-sulfo Lewis X is inversely correlated with conventional sialyl Lewis X expression in human colorectal cancer. Cancer Res. 2000 Mar 1;60(5):1410-6 PMID: 10728707 |
| 3 | Uchimura K, Muramatsu H, Kadomatsu K, Fan QW, Kurosawa N, Mitsuoka C, Kannagi R, Habuchi O, Muramatsu T. Molecular cloning and characterization of an N-acetylglucosamine-6-O-sulfotransferase. J Biol Chem. 1998 Aug 28;273(35):22577-83 PMID: 9712885 |
| 4 | Kimura N, Mitsuoka C, Kanamori A, Hiraiwa N, Uchimura K, Muramatsu T, Tamatani T, Kansas GS, Kannagi R. Reconstitution of functional L-selectin ligands on a cultured human endothelial cell line by cotransfection of alpha1-->3 fucosyltransferase VII and newly cloned GlcNAcbeta:6-sulfotransferase cDNA. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4530-5 PMID: 10200296 |