ACFH-18
| Antibody ID | AN0240 |
|---|
| Epitope ID | EP0212 |
|---|---|
| Epitope name | Internal Lewis x |
| Recognition region | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer |
| Immunoprecipitation | |
| Immunoblot | [2*][3] |
| ELISA/RIA | [2*][1*] |
| Flow cytometry | |
| Histochemistry | [3] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | MKN74/human gastric carcinoma[2*] |
| Availability | |
| Applications |
| 1 | Fukushi Y, Hakomori S, Nudelman E, Cochran N. Novel fucolipids accumulating in human adenocarcinoma. II. Selective isolation of hybridoma antibodies that differentially recognize mono-, di-, and trifucosylated type 2 chain. J Biol Chem. 1984 Apr 10;259(7):4681-5 PMID: 6200484 |
|---|---|
| 2 | Nudelman ED, Levery SB, Stroud MR, Salyan ME, Abe K, Hakomori S. A novel tumor-associated, developmentally regulated glycolipid antigen defined by monoclonal antibody ACFH-18. J Biol Chem. 1988 Sep 25;263(27):13942-51 PMID: 3417685 |
| 3 | Dohi T, Abe K, Ohshiba S, Yamaguchi K, Oshima M. Immunohistological and biochemical detection of fucosylated polylactosamine antigen with monoclonal antibody ACFH18 in gastric cancer and normal gastric mucosa. Jpn J Cancer Res. 1990 Jun ;81(6-7):676-81 PMID: 2119368 |