YB-2

Antibody IDAN0514
Epitope ID EP0010
Epitope nameLewis b
Recognition regionFuc(a1-2)Gal(b1-4)[Fuc(a1-3)]GlcNAc-(b1-)-R
Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-)-R
Fuc(a1-2)Gal(b1-4)GlcNAc(b1-)-R
Immunoprecipitation
Immunoblot
ELISA/RIA[4]
Flow cytometry[3]
Histochemistry[1][2][3]
Comment
Epitope ID EP0018
Epitope nameLewis y
Recognition regionFuc(a1-2)Gal(b1-4)[Fuc(a1-3)]GlcNAc-(b1-)-R
Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-)-R
Fuc(a1-2)Gal(b1-4)GlcNAc(b1-)-R
Immunoprecipitation
Immunoblot
ELISA/RIA[4]
Flow cytometry[3]
Histochemistry[1][2][3]
Comment
Epitope ID EP0252
Epitope nameBlood Group H Type 2
Recognition regionFuc(a1-2)Gal(b1-4)[Fuc(a1-3)]GlcNAc-(b1-)-R
Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-)-R
Fuc(a1-2)Gal(b1-4)GlcNAc(b1-)-R
Immunoprecipitation
Immunoblot
ELISA/RIA[4]
Flow cytometry[3]
Histochemistry[1][2][3]
Comment
SpeciesMouse
CategoryMonoclonal
Isotype-
Immunogen
Availability
Applications
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1 Yazawa S, Akamatsu S, Tachikawa T, Naito H, Nakamura J, Asao T, Nagamachi Y, Nakajima T, Shin S, Chia D.
Development and characterization of a novel anti-fucosylated antigen monoclonal antibody YB-2 and its usefulness in the immunohistochemical diagnosis of colorectal cancer.
Jpn J Cancer Res. 1993 Jun ;84(6):641-8
PMID: 8340252
2 Naitoh H, Yazawa S, Asao T, Nakajima T, Nakamura J, Takenoshita S, Nagamachi Y.
The recognition of cancer-associated fucosylated antigens in colorectal cancer by a novel monoclonal antibody, YB-2.
Surg Today. 1994 ;24(4):382-4
PMID: 8038519
3 Yazawa S, Nishimura T, Ide M, Asao T, Okamura A, Tanaka S, Takai I, Yagihashi Y, Saniabadi AR, Kochibe N.
Tumor-related expression of alpha1,2fucosylated antigens on colorectal carcinoma cells and its suppression by cell-mediated priming using sugar acceptors for alpha1,2fucosyltransferase.
Glycobiology. 2002 Sep ;12(9):545-53
PMID: 12213787
4 Nakamura J, Yazawa S, Hada T, Asao T, Naitoh H, Takenoshita S, Kosaka M, Akamatsu S, Tachikawa T, Nagamachi Y.
The usefulness of anti-fucosylated antigen antibody YB-2 for diagnosis of hepatocellular carcinoma.
Glycoconj J. 1997 Jan ;14(1):81-7
PMID: 9076517