MBr1
| Antibody ID | AN0478 |
|---|
| Epitope ID | EP0253 |
|---|---|
| Epitope name | Blood Group H Type 3 |
| Recognition region | Fuc(a1-2)Gal(b1-3)GalNAc(a1-)-R Fuc(a1-2)Gal(b1-3)GalNAc(b1-)-R |
| Immunoprecipitation | |
| Immunoblot | [2*][1] |
| ELISA/RIA | |
| Flow cytometry | |
| Histochemistry | |
| Comment |
| Epitope ID | EP0254 |
|---|---|
| Epitope name | Blood Group H Type 4 |
| Recognition region | Fuc(a1-2)Gal(b1-3)GalNAc(a1-)-R Fuc(a1-2)Gal(b1-3)GalNAc(b1-)-R |
| Immunoprecipitation | |
| Immunoblot | [2*][3][4*][1] |
| ELISA/RIA | [4*] |
| Flow cytometry | |
| Histochemistry | [3] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | MCF-7/human breast adenocarcinoma[5] |
| Availability | |
| Applications |
| 1 | Clausen H, Levery SB, Nudelman E, Tsuchiya S, Hakomori S. Repetitive A epitope (type 3 chain A) defined by blood group A1-specific monoclonal antibody TH-1: chemical basis of qualitative A1 and A2 distinction. Proc Natl Acad Sci U S A. 1985 Feb ;82(4):1199-203 PMID: 2579390 |
|---|---|
| 2 | Clausen H, Levery SB, Kannagi R, Hakomori S. Novel blood group H glycolipid antigens exclusively expressed in blood group A and AB erythrocytes (type 3 chain H). I. Isolation and chemical characterization. J Biol Chem. 1986 Jan 25;261(3):1380-7 PMID: 3944091 |
| 3 | Okada Y, Colnaghi MI, Tsuji T. Type 4 chain H expression by bile ductules and hepatocytes in cirrhosis. J Pathol. 1989 Apr ;157(4):329-38 PMID: 2469783 |
| 4 | Bremer EG, Levery SB, Sonnino S, Ghidoni R, Canevari S, Kannagi R, Hakomori S. Characterization of a glycosphingolipid antigen defined by the monoclonal antibody MBr1 expressed in normal and neoplastic epithelial cells of human mammary gland. J Biol Chem. 1984 Dec 10;259(23):14773-7 PMID: 6501317 |
| 5 | Mènard S, Tagliabue E, Canevari S, Fossati G, Colnaghi MI. Generation of monoclonal antibodies reacting with normal and cancer cells of human breast. Cancer Res. 1983 Mar ;43(3):1295-300 PMID: 6337705 |