TL5

Antibody IDAN0579
Epitope ID EP0256
Epitope nameBlood Group A Type 1
Recognition regionGalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc(b1-)-R
GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-)-R
Immunoprecipitation[2*]
Immunoblot[1]
ELISA/RIA[3]
Flow cytometry
Histochemistry
Comment
Epitope ID EP0257
Epitope nameBlood Group A Type 2
Recognition regionGalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc(b1-)-R
GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-)-R
Immunoprecipitation[2*]
Immunoblot[1]
ELISA/RIA[3]
Flow cytometry
Histochemistry
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgG
ImmunogenA431/human epidermoid carcinoma[4][2*]
Availability
Applications
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1 Childs RA, Gregoriou M, Scudder P, Thorpe SJ, Rees AR, Feizi T.
Blood group-active carbohydrate chains on the receptor for epidermal growth factor of A431 cells.
EMBO J. 1984 Oct ;3(10):2227-33
PMID: 6094178
2 Schreiber AB, Libermann TA, Lax I, Yarden Y, Schlessinger J.
Biological role of epidermal growth factor-receptor clustering. Investigation with monoclonal anti-receptor antibodies.
J Biol Chem. 1983 Jan 25;258(2):846-53
PMID: 6296087
3 Gooi HC, Schlessinger J, Lax I, Yarden Y, Libermann TA, Feizi T.
Monoclonal antibody reactive with the human epidermal-growth-factor receptor recognizes the blood-group-A antigen.
Biosci Rep. 1983 Nov ;3(11):1045-52
PMID: 6198005
4 Schreiber AB, Lax I, Yarden Y, Eshhar Z, Schlessinger J.
Monoclonal antibodies against receptor for epidermal growth factor induce early and delayed effects of epidermal growth factor.
Proc Natl Acad Sci U S A. 1981 Dec ;78(12):7535-9
PMID: 6278478