M2590

Antibody IDAN0372
Epitope ID EP0053
Epitope nameN-Acetyl GM3
Recognition regionNeu5Ac(a2-3)Gal(b1-4)Glc-R
Neu5Ac(a2-3)Gal(b1-4)GlcNAc-R
Immunoprecipitation
Immunoblot[1*]
ELISA/RIA[1*][2]
Flow cytometry
Histochemistry
Comment
Epitope ID EP0076
Epitope name2-3 Sialylparagloboside
Recognition regionNeu5Ac(a2-3)Gal(b1-4)Glc-R
Neu5Ac(a2-3)Gal(b1-4)GlcNAc-R
Immunoprecipitation
Immunoblot[1*]
ELISA/RIA
Flow cytometry
Histochemistry
Comment
Epitope ID EP0305
Epitope nameNeu5Ac(a2-3)Gal(b1-4)Glc
Recognition regionNeu5Ac(a2-3)Gal(b1-4)Glc-R
Neu5Ac(a2-3)Gal(b1-4)GlcNAc-R
Immunoprecipitation
Immunoblot[1*]
ELISA/RIA[1*]
Flow cytometry
Histochemistry
Comment
Epitope ID EP0314
Epitope nameNeu5Ac(a2-3)Gal(b1-4)GlcNAc
Recognition regionNeu5Ac(a2-3)Gal(b1-4)Glc-R
Neu5Ac(a2-3)Gal(b1-4)GlcNAc-R
Immunoprecipitation
Immunoblot[1*]
ELISA/RIA[1*]
Flow cytometry
Histochemistry
Comment
SpeciesMouse
CategoryMonoclonal
IsotypeIgM
Immunogen
AvailabilityNIPPON BIO-TEST LABORATORIES INC.
Applications
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1 Hirabayashi Y, Hamaoka A, Matsumoto M, Matsubara T, Tagawa M, Wakabayashi S, Taniguchi M.
Syngeneic monoclonal antibody against melanoma antigen with interspecies cross-reactivity recognizes GM3, a prominent ganglioside of B16 melanoma.
J Biol Chem. 1985 Oct 25;260(24):13328-33
PMID: 2414279
2 Dohi T, Nores G, Hakomori S.
An IgG3 monoclonal antibody established after immunization with GM3 lactone: immunochemical specificity and inhibition of melanoma cell growth in vitro and in vivo.
Cancer Res. 1988 Oct 15;48(20):5680-5
PMID: 3167827