DMAb-1
| Antibody ID | AN0504 |
|---|
| Epitope ID | EP0051 |
|---|---|
| Epitope name | N-Acetyl GM2 |
| Recognition region | GalNAc(b1-4)[Neu5Ac(a2-3)]Gal-R |
| Immunoprecipitation | |
| Immunoblot | [2][3] |
| ELISA/RIA | [2][3] |
| Flow cytometry | |
| Histochemistry | [4] |
| Comment |
| Epitope ID | EP0311 |
|---|---|
| Epitope name | GalNAc(b1-4)[Neu5Ac(a2-3)]Gal(b1) |
| Recognition region | GalNAc(b1-4)[Neu5Ac(a2-3)]Gal-R |
| Immunoprecipitation | |
| Immunoblot | [2][3] |
| ELISA/RIA | [2][3] |
| Flow cytometry | |
| Histochemistry | [4] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | |
| Availability | |
| Applications | TLC-ELISA[1*] |
| 1 | Fredman P, Mansson JE, Wikstrand CJ, Vrionis FD, Rynmark BM, Bigner DD, Svennerholm L. A new ganglioside of the lactotetraose series, GalNAc-3'-isoLM1, detected in human meconium. J Biol Chem. 1989 Jul 25;264(21):12122-5 PMID: 2473071 |
|---|---|
| 2 | Karlsson G, Mansson JE, Wikstrand C, Bigner D, Svennerholm L. Characterization of the binding epitope of the monoclonal antibody DMAb-1 to ganglioside GM2. Biochim Biophys Acta. 1990 Apr 17;1043(3):267-72 PMID: 1691018 |
| 3 | Vrionis FD, Wikstrand CJ, Fredman P, Mansson JE, Svennerholm L, Bigner DD. Five new epitope-defined monoclonal antibodies reactive with GM2 and human glioma and medulloblastoma cell lines. Cancer Res. 1989 Dec 1;49(23):6645-51 PMID: 2479468 |
| 4 | Hedberg KM, Mahesparan R, Read TA, Tysnes BB, Thorsen F, Visted T, Bjerkvig R, Fredman P. The glioma-associated gangliosides 3'-isoLM1, GD3 and GM2 show selective area expression in human glioblastoma xenografts in nude rat brains. Neuropathol Appl Neurobiol. 2001 Dec ;27(6):451-64 PMID: 11903928 |