6,6'- Disulfo Sialyl Lewis x

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

Epitope information of EP0016

Epitope IDEP0016
Epitope name6,6'- Disulfo Sialyl Lewis x
Structure
SequenceNeu5Ac(a2-3)[HSO3(-6)]Gal(b1-4)[Fuc(a1-3)][HSO3(-6)]GlcNAc(b1-)-R
Aliases6,6'-Disulfo Sialyl Lex
History6'- Sulfo Sialyl Lex and 6,6'- Disulfo Sialyl Lex are L-selectin ligand on HEV of mice.[11*][12]
The term Lewis refers to the family name of individuals suffering from a red blood cell incompatibility problem that helped lead to the discovery of this blood group.
DB
Molecular weight980.9
Composition(Fuc)1(Gal)1(GlcNAc)1(Neu5Ac)1(HSO3)2
Species

Mus musculus

Tissue and Cellular distribution

HEV(mouse)

Subcellular distribution

Developmental change

Cell line

Receptor

L-selectin(mouse)(The hierarchy of binding strengths were 6-sulfo sialyl > sialyl = 6',6-bis-sulfo sialyl >> 6'-sulfo sialyl Lex.)[23][12][11*]

Function

lymphocyte homing

Diseases

Application
Comment