Tn Antigen
General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference104 reference for EP0021
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46 | Wong ET, Lindall AW. Subcellular location of human parathyroid hormone immunoreactive peptides and preliminary evidence for a precursor to human PTH-1 (38545). Proc Soc Exp Biol Med. 1975 Feb ;148(2):387-92 PMID: 1121486 |
37 | Nurden AT, Dupuis D, Pidard D, Kieffer N, Kunicki TJ, Cartron JP. Surface modifications in the platelets of a patient with alpha-N-acetyl-D-galactosamine residues, the Tn-syndrome. J Clin Invest. 1982 Dec ;70(6):1281-91 PMID: 7174794 |
38 | Vainchenker W, Testa U, Deschamps JF, Henri A, Titeux M, Breton-Gorius J, Rochant H, Lee D, Cartron JP. Clonal expression of the Tn antigen in erythroid and granulocyte colonies and its application to determination of the clonality of the human megakaryocyte colony assay. J Clin Invest. 1982 May ;69(5):1081-91 PMID: 6175663 |
20 | Springer GF, Taylor CR, Howard DR, Tegtmeyer H, Desai PR, Murthy SM, Felder B, Scanlon EF. Tn, a carcinoma-associated antigen, reacts with anti-Tn of normal human sera. Cancer. 1985 Feb 1;55(3):561-9 PMID: 2981150 |
31 | Hirohashi S, Clausen H, Yamada T, Shimosato Y, Hakomori S. Blood group A cross-reacting epitope defined by monoclonal antibodies NCC-LU-35 and -81 expressed in cancer of blood group O or B individuals: its identification as Tn antigen. Proc Natl Acad Sci U S A. 1985 Oct ;82(20):7039-43 PMID: 2413456 |
76 | Longenecker BM, Willans DJ, MacLean GD, Selvaraj S, Suresh MR, Noujaim AA. Monoclonal antibodies and synthetic tumor-associated glycoconjugates in the study of the expression of Thomsen-Friedenreich-like and Tn-like antigens on human cancers. J Natl Cancer Inst. 1987 Mar ;78(3):489-96 PMID: 3469463 |
28 | Roxby DJ, Morley AA, Burpee M. Detection of the Tn antigen in leukaemia using monoclonal anti-Tn antibody and immunohistochemistry. Br J Haematol. 1987 Oct ;67(2):153-6 PMID: 3479188 |
34 | Kjeldsen T, Clausen H, Hirohashi S, Ogawa T, Iijima H, Hakomori S. Preparation and characterization of monoclonal antibodies directed to the tumor-associated O-linked sialosyl-2----6 alpha-N-acetylgalactosaminyl (sialosyl-Tn) epitope. Cancer Res. 1988 Apr 15;48(8):2214-20 PMID: 2450649 |
27 | Takahashi HK, Metoki R, Hakomori S. Immunoglobulin G3 monoclonal antibody directed to Tn antigen (tumor-associated alpha-N-acetylgalactosaminyl epitope) that does not cross-react with blood group A antigen. Cancer Res. 1988 Aug 1;48(15):4361-7 PMID: 3390832 |
26 | Natali PG, Nicotra MR, Nuti M, Bigotti G, Calabro A, Schlom J, Giacomini P. Molecular profile, tissue distribution and prognostic evaluation of a human melanoma-carcinoma antigen recognized by the murine monoclonal antibody B1.1. Int J Biol Markers. 1988 Oct ;3(4):211-20 PMID: 3235849 |
21 | Springer GF. Tn epitope (N-acetyl-D-galactosamine alpha-O-serine/threonine) density in primary breast carcinoma: a functional predictor of aggressiveness. Mol Immunol. 1989 Jan ;26(1):1-5 PMID: 2467192 |
1 | Itzkowitz SH, Yuan M, Montgomery CK, Kjeldsen T, Takahashi HK, Bigbee WL, Kim YS. Expression of Tn, sialosyl-Tn, and T antigens in human colon cancer. Cancer Res. 1989 Jan 1;49(1):197-204 PMID: 2908846 |
68 | Piller V, Piller F, Fukuda M. Biosynthesis of truncated O-glycans in the T cell line Jurkat. Localization of O-glycan initiation. J Biol Chem. 1990 Jun 5;265(16):9264-71 PMID: 2140570 |
47 | King MJ, Parsons SF, Wu AM, Jones N. Immunochemical studies on the differential binding properties of two monoclonal antibodies reacting with Tn red cells. Transfusion. 1991 Feb ;31(2):142-9 PMID: 1847560 |
9 | Schuessler MH, Pintado S, Welt S, Real FX, Xu M, Melamed MR, Lloyd KO, Oettgen HF. Blood group and blood-group-related antigens in normal pancreas and pancreas cancer: enhanced expression of precursor type 1, Tn and sialyl-Tn in pancreas cancer. Int J Cancer. 1991 Jan 21;47(2):180-7 PMID: 1988363 |
36 | Singhal A, Fohn M, Hakomori S. Induction of alpha-N-acetylgalactosamine-O-serine/threonine (Tn) antigen-mediated cellular immune response for active immunotherapy in mice. Cancer Res. 1991 Mar 1;51(5):1406-11 PMID: 1997178 |
40 | Nakada H, Inoue M, Numata Y, Tanaka N, Funakoshi I, Fukui S, Yamashina I. Cancer-associated glycoproteins defined by a monoclonal antibody, MLS 128, recognizing the Tn antigen. Biochem Biophys Res Commun. 1992 Aug 31;187(1):217-24 PMID: 1520302 |
42 | Charpin C, Pancino G, Osinaga E, Bonnier P, Lavaut MN, Allasia C, Roseto A. Monoclonal antibody 83D4 immunoreactivity in human tissues: cellular distribution and microcytophotometric analysis of immunoprecipitates on tissue sections. Anticancer Res. 1992 Jan ;12(1):209-23 PMID: 1567169 |
32 | Duk M, Steuden I, Dus D, Radzikowski C, Lisowska E. Application of chemically desialylated and degalactosylated human glycophorin for induction and characterization of anti-Tn monoclonal antibodies. Glycoconj J. 1992 Jun ;9(3):148-53 PMID: 1422133 |
29 | Roxby DJ, Pfeiffer MB, Morley AA, Kirkland MA. Expression of the Tn antigen in myelodysplasia, lymphoma, and leukemia. Transfusion. 1992 Nov ;32(9):834-8 PMID: 1471247 |
41 | Blumenfeld OO, Lalezari P, Khorshidi M, Puglia K, Fukuda M. O-linked oligosaccharides of glycophorins A and B in erythrocytes of two individuals with the Tn polyagglutinability syndrome. Blood. 1992 Nov 1;80(9):2388-95 PMID: 1421410 |
24 | Thurnher M, Clausen H, Sharon N, Berger EG. Use of O-glycosylation-defective human lymphoid cell lines and flow cytometry to delineate the specificity of Moluccella laevis lectin and monoclonal antibody 5F4 for the Tn antigen (GalNAc alpha 1-O-Ser/Thr). Immunol Lett. 1993 Jun ;36(3):239-43 PMID: 8370596 |
89 | Nakada H, Inoue M, Numata Y, Tanaka N, Funakoshi I, Fukui S, Mellors A, Yamashina I. Epitopic structure of Tn glycophorin A for an anti-Tn antibody (MLS 128). Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2495-9 PMID: 7681597 |
73 | Thurnher M, Rusconi S, Berger EG. Persistent repression of a functional allele can be responsible for galactosyltransferase deficiency in Tn syndrome. J Clin Invest. 1993 May ;91(5):2103-10 PMID: 7683697 |
39 | Thurnher M, Wagner E, Clausen H, Mechtler K, Rusconi S, Dinter A, Birnstiel ML, Berger EG, Cotten M. Carbohydrate receptor-mediated gene transfer to human T leukaemic cells. Glycobiology. 1994 Aug ;4(4):429-35 PMID: 7827404 |
22 | Inoue M, Nakada H, Tanaka N, Yamashina I. Tn antigen is expressed on leukosialin from T-lymphoid cells. Cancer Res. 1994 Jan 1;54(1):85-8 PMID: 8261467 |
14 | Nakada H, Inoue M, Tanaka N, Yamashina I. Coexpression of cancer-associated carbohydrate antigens, Tn and sialyl Tn. Glycoconj J. 1994 Jun ;11(3):262-5 PMID: 7841802 |
35 | King MJ, Chan A, Roe R, Warren BF, Dell A, Morris HR, Bartolo DC, Durdey P, Corfield AP. Two different glycosyltransferase defects that result in GalNAc alpha-O-peptide (Tn) expression. Glycobiology. 1994 Jun ;4(3):267-79 PMID: 7949653 |
3 | Reed W, Bryne M, Clausen H, Dabelsteen E, Nesland JM. Simple mucins (T, sialosyl-T, Tn and sialosyl-Tn) are not diagnostic for malignant breast lesions. Anticancer Res. 1994 Mar ;14(2B):609-15 PMID: 7516636 |
30 | Ohshio G, Imamura T, Imamura M, Yamabe H, Sakahara H, Nakada H, Yamashina I. Distribution of Tn antigen recognized by an anti-Tn monoclonal antibody (MLS128) in normal and malignant tissues of the digestive tract. J Cancer Res Clin Oncol. 1995 ;121(4):247-52 PMID: 7751324 |
18 | Yao Z, Sakahara H, Zhang M, Kobayashi H, Nakada H, Yamashina I, Konishi J. Radioimmunoimaging of colon cancer xenografts with anti-Tn monoclonal antibody. Nucl Med Biol. 1995 Feb ;22(2):199-203 PMID: 7767313 |
11 | Ogawa H, Ghazizadeh M, Araki T. Tn and sialyl-Tn antigens as potential prognostic markers in human ovarian carcinoma. Gynecol Obstet Invest. 1996 ;41(4):278-83 PMID: 8793500 |
5 | Wang BL, Springer GF, Kaufman MW. Concurrent immunohistochemical staining of tumor-infiltrating lymphocytes and carcinoma-associated T (Thomsen-Friedenreich)/Tn antigens in human breast carcinoma. J Histochem Cytochem. 1996 Feb ;44(2):187-91 PMID: 8609376 |
10 | Terada T, Nakanuma Y. Expression of mucin carbohydrate antigens (T, Tn and sialyl Tn) and MUC-1 gene product in intraductal papillary-mucinous neoplasm of the pancreas. Am J Clin Pathol. 1996 May ;105(5):613-20 PMID: 8623771 |
12 | Terasawa K, Furumoto H, Kamada M, Aono T. Expression of Tn and sialyl-Tn antigens in the neoplastic transformation of uterine cervical epithelial cells. Cancer Res. 1996 May 1;56(9):2229-32 PMID: 8616877 |
7 | Avichezer D, Springer GF, Schechter B, Arnon R. Immunoreactivities of polyclonal and monoclonal anti-T and anti-Tn antibodies with human carcinoma cells, grown in vitro and in a xenograft model. Int J Cancer. 1997 Jul 3;72(1):119-27 PMID: 9212232 |
2 | Zhang S, Zhang HS, Cordon-Cardo C, Reuter VE, Singhal AK, Lloyd KO, Livingston PO. Selection of tumor antigens as targets for immune attack using immunohistochemistry: II. Blood group-related antigens. Int J Cancer. 1997 Sep 26;73(1):50-6 PMID: 9334809 |
50 | Giuffre G, Vitarelli E, Tuccari G, Barresi G. Immunohistochemical study of Tn, sialosyl-Tn and T antigens in human meningiomas. Eur J Histochem. 1998 ;42(3):197-203 PMID: 9857245 |
74 | Felner KM, Dinter A, Cartron JP, Berger EG. Repressed beta-1,3-galactosyltransferase in the Tn syndrome. Biochim Biophys Acta. 1998 Feb 27;1406(1):115-25 PMID: 9545556 |
44 | Croce MV, Colussi AG, Price MR, Segal-Eiras A. Identification and characterization of different subpopulations in a human lung adenocarcinoma cell line (A549). Pathol Oncol Res. 1999 ;5(3):197-204 PMID: 10491017 |
6 | Sasaki M, Yamato T, Nakanuma Y. Expression of sialyl-Tn, Tn and T antigens in primary liver cancer. Pathol Int. 1999 Apr ;49(4):325-31 PMID: 10365852 |
72 | Berger EG. Tn-syndrome. Biochim Biophys Acta. 1999 Oct 8;1455(2-3):255-68 PMID: 10571017 |
16 | Takano Y, Teranishi Y, Terashima S, Motoki R, Kawaguchi T. Lymph node metastasis-related carbohydrate epitopes of gastric cancer with submucosal invasion. Surg Today. 2000 ;30(12):1073-82 PMID: 11193738 |
25 | Croce MV, Rabassa ME, Price MR, Segal-Eiras A. MUC1 mucin and carbohydrate associated antigens as tumor markers in head and neck squamous cell carcinoma. Pathol Oncol Res. 2001 ;7(4):284-91 PMID: 11882908 |
17 | Alvarez Errico D, Medeiros A, Miguez M, Casaravilla C, Malgor R, Carmona C, Nieto A, Osinaga E. O-glycosylation in Echinococcus granulosus: identification and characterization of the carcinoma-associated Tn antigen. Exp Parasitol. 2001 Jun ;98(2):100-9 PMID: 11465993 |
4 | Imai J, Ghazizadeh M, Naito Z, Asano G. Immunohistochemical expression of T, Tn and sialyl-Tn antigens and clinical outcome in human breast carcinoma. Anticancer Res. 2001 Mar ;21(2B):1327-34 PMID: 11396208 |
13 | Ogata S, Ho I, Maklansky J, Chen A, Werther JL, Reddish M, Longenecker BM, Sigurdson E, Iishi S, Zhang JY, Itzkowitz SH. A rat model to study the role of STn antigen in colon cancer. Glycoconj J. 2001 Nov ;18(11-12):871-82 PMID: 12820721 |
102 | Julien S, Krzewinski-Recchi MA, Harduin-Lepers A, Gouyer V, Huet G, Le Bourhis X, Delannoy P. Expression of sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase (ST6GalNac I) cDNA. Glycoconj J. 2001 Nov ;18(11-12):883-93 PMID: 12820722 |
23 | Akita K, Fushiki S, Fujimoto T, Inoue M, Oguri K, Okayama M, Yamashina I, Nakada H. Developmental expression of a unique carbohydrate antigen, Tn antigen, in mouse central nervous tissues. J Neurosci Res. 2001 Sep 15;65(6):595-603 PMID: 11550228 |
33 | Grinstead JS, Koganty RR, Krantz MJ, Longenecker BM, Campbell AP. Effect of glycosylation on MUC1 humoral immune recognition: NMR studies of MUC1 glycopeptide-antibody interactions. Biochemistry. 2002 Aug 6;41(31):9946-61 PMID: 12146959 |
43 | Casaravilla C, Freire T, Malgor R, Medeiros A, Osinaga E, Carmona C. Mucin-type O-glycosylation in helminth parasites from major taxonomic groups: evidence for widespread distribution of the Tn antigen (GalNAc-Ser/Thr) and identification of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity. J Parasitol. 2003 Aug ;89(4):709-14 PMID: 14533679 |
8 | Freire T, Casaravilla C, Carmona C, Osinaga E. Mucin-type O-glycosylation in Fasciola hepatica: characterisation of carcinoma-associated Tn and sialyl-Tn antigens and evaluation of UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase activity. Int J Parasitol. 2003 Jan ;33(1):47-56 PMID: 12547345 |
80 | Yoshida T, Tsuruta Y, Iwasaki M, Yamane S, Ochi T, Suzuki R. SRCL/CL-P1 recognizes GalNAc and a carcinoma-associated antigen, Tn antigen. J Biochem. 2003 Mar ;133(3):271-7 PMID: 12761161 |
19 | Freire T, Medeiros A, Reis CA, Real FX, Osinaga E. Biochemical characterization of soluble Tn glycoproteins from malignant effusions of patients with carcinomas. Oncol Rep. 2003 Sep ;10(5):1577-85 PMID: 12883744 |
90 | Zheng M, Ruan Y, Yang M, Guan Y, Wu Z. The comparative study on ultrastructure and immunohistochemistry in AFP negative and positive hepatocellular carcinoma. J Huazhong Univ Sci Technolog Med Sci. 2004 ;24(6):547-9, 559 PMID: 15791836 |
92 | Sakuraba H, Matsuzawa F, Aikawa S, Doi H, Kotani M, Nakada H, Fukushige T, Kanzaki T. Structural and immunocytochemical studies on alpha-N-acetylgalactosaminidase deficiency (Schindler/Kanzaki disease). J Hum Genet. 2004 ;49(1):1-8 PMID: 14685826 |
81 | Wu AM, Wu JH, Liu JH, Singh T. Recognition profile of Bauhinia purpurea agglutinin (BPA). Life Sci. 2004 Feb 20;74(14):1763-79 PMID: 14741734 |
15 | Linden S, Boren T, Dubois A, Carlstedt I. Rhesus monkey gastric mucins: oligomeric structure, glycoforms and Helicobacter pylori binding. Biochem J. 2004 May 1;379(Pt 3):765-75 PMID: 14736333 |
87 | Sotiriadis J, Shin SC, Yim D, Sieber D, Kim YB. Thomsen-Friedenreich (T) antigen expression increases sensitivity of natural killer cell lysis of cancer cells. Int J Cancer. 2004 Sep 1;111(3):388-97 PMID: 15221966 |
48 | Wua AM, Wub JH, Kuoa HW, Herpa A. Further characterization of the binding properties of two monoclonal antibodies recognizing human Tn red blood cells. J Biomed Sci. 2005 ;12(1):153-66 PMID: 15864747 |
85 | Wu AM. Polyvalent GalNAcalpha1-->Ser/Thr (Tn) and Galbeta1-->3GalNAcalpha1-->Ser/Thr (T alpha) as the most potent recognition factors involved in Maclura pomifera agglutinin-glycan interactions. J Biomed Sci. 2005 ;12(1):135-52 PMID: 15864746 |
96 | Wu AM. Lectinochemical studies on the glyco-recognition factors of a Tn (GalNAcalpha1-->Ser/Thr) specific lectin isolated from the seeds of Salvia sclarea. J Biomed Sci. 2005 ;12(1):167-84 PMID: 15864748 |
65 | Natsuka S, Kawaguchi M, Wada Y, Ichikawa A, Ikura K, Hase S. Characterization of wheat germ agglutinin ligand on soluble glycoproteins in Caenorhabditis elegans. J Biochem. 2005 Aug ;138(2):209-13 PMID: 16091596 |
71 | Kawaguchi T, Takazawa H, Imai S, Morimoto J, Watanabe T. Lack of polymorphism in MUC1 tandem repeats in cancer cells is related to breast cancer progression in Japanese women. Breast Cancer Res Treat. 2005 Aug ;92(3):223-30 PMID: 16155793 |
97 | Manimala JC, Li Z, Jain A, VedBrat S, Gildersleeve JC. Carbohydrate array analysis of anti-Tn antibodies and lectins reveals unexpected specificities: implications for diagnostic and vaccine development. Chembiochem. 2005 Dec ;6(12):2229-41 PMID: 16252298 |
99 | Kulkarni KA, Sinha S, Katiyar S, Surolia A, Vijayan M, Suguna K. Structural basis for the specificity of basic winged bean lectin for the Tn-antigen: a crystallographic, thermodynamic and modelling study. FEBS Lett. 2005 Dec 19;579(30):6775-80 PMID: 16310781 |
55 | Berriel E, Hill M, Barcia JJ, Ubillos L, Gonzalez M, Detjen G, Rondan M, Navarrete H, Osinaga E. Simple mucin-type cancer associated antigens are pre-cancerous biomarkers during 1,2-dimethylhydrazine-induced rat colon carcinogenesis. Oncol Rep. 2005 Jul ;14(1):219-27 PMID: 15944793 |
45 | Jorgensen-Tye B, Levesque JP, Royle L, Doyonnas R, Chan JY, Dwek RA, Rudd PM, Harvey DJ, Simmons PJ, Watt SM. Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesis. Tissue Antigens. 2005 Mar ;65(3):220-39 PMID: 15730515 |
51 | Ragupathi G, Liu NX, Musselli C, Powell S, Lloyd K, Livingston PO. Antibodies against tumor cell glycolipids and proteins, but not mucins, mediate complement-dependent cytotoxicity. J Immunol. 2005 May 1;174(9):5706-12 PMID: 15843572 |
49 | Kumar SR, Sauter ER, Quinn TP, Deutscher SL. Thomsen-Friedenreich and Tn antigens in nipple fluid: carbohydrate biomarkers for breast cancer detection. Clin Cancer Res. 2005 Oct 1;11(19 Pt 1):6868-71 PMID: 16203776 |
54 | Ju T, Cummings RD. Protein glycosylation: chaperone mutation in Tn syndrome. Nature. 2005 Oct 27;437(7063):1252 PMID: 16251947 |
69 | Freire T, Bay S, von Mensdorff-Pouilly S, Osinaga E. Molecular basis of incomplete O-glycan synthesis in MCF-7 breast cancer cells: putative role of MUC6 in Tn antigen expression. Cancer Res. 2005 Sep 1;65(17):7880-7 PMID: 16140958 |
75 | Yano H, Yamamoto-Hino M, Abe M, Kuwahara R, Haraguchi S, Kusaka I, Awano W, Kinoshita-Toyoda A, Toyoda H, Goto S. Distinct functional units of the Golgi complex in Drosophila cells. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13467-72 PMID: 16174741 |
61 | Paszkiewicz-Gadek A, Porowska H, Lemancewicz D, Wolczynski S, Gindzienski A. The influence of N- and O-glycosylation inhibitors on the glycosylation profile of cellular membrane proteins and adhesive properties of carcinoma cell lines. Int J Mol Med. 2006 Apr ;17(4):669-74 PMID: 16525726 |
66 | Konska G, Guerry M, Caldefie-Chezet F, De Latour M, Guillot J. Study of the expression of Tn antigen in different types of human breast cancer cells using VVA-B4 lectin. Oncol Rep. 2006 Feb ;15(2):305-10 PMID: 16391846 |
95 | Vega N, Pérez G. Isolation and characterisation of a Salvia bogotensis seed lectin specific for the Tn antigen. Phytochemistry. 2006 Feb ;67(4):347-55 PMID: 16413042 |
84 | Tachibana K, Nakamura S, Wang H, Iwasaki H, Tachibana K, Maebara K, Cheng L, Hirabayashi J, Narimatsu H. Elucidation of binding specificity of Jacalin toward O-glycosylated peptides: quantitative analysis by frontal affinity chromatography. Glycobiology. 2006 Jan ;16(1):46-53 PMID: 16177266 |
52 | Kawaguchi T, Takazawa H, Imai S, Morimoto J, Watanabe T, Kanno M, Igarashi S. Expression of Vicia villosa agglutinin (VVA)-binding glycoprotein in primary breast cancer cells in relation to lymphatic metastasis: is atypical MUC1 bearing Tn antigen a receptor of VVA? Breast Cancer Res Treat. 2006 Jul ;98(1):31-43 PMID: 16752227 |
59 | Wu WC, Lai CC, Liu JH, Singh T, Li LM, Peumans WJ, Van Damme EJ, Wu AM. Differential binding to glycotopes among the layers of three mammalian retinal neurons by man-containing N-linked glycan, T(alpha) (Galbeta1-3GalNAcalpha1-), Tn (GalNAcalpha1-Ser/Thr) and I (beta)/II (beta) (Galbeta1-3/4GlcNAcbeta-) reactive lectins. Neurochem Res. 2006 May ;31(5):619-28 PMID: 16770733 |
101 | Wearne KA, Winter HC, O'Shea K, Goldstein IJ. Use of lectins for probing differentiated human embryonic stem cells for carbohydrates. Glycobiology. 2006 Oct ;16(10):981-90 PMID: 16809438 |
53 | Schietinger A, Philip M, Yoshida BA, Azadi P, Liu H, Meredith SC, Schreiber H. A mutant chaperone converts a wild-type protein into a tumor-specific antigen. Science. 2006 Oct 13;314(5797):304-8 PMID: 17038624 |
56 | Pinho S, Marcos NT, Ferreira B, Carvalho AS, Oliveira MJ, Santos-Silva F, Harduin-Lepers A, Reis CA. Biological significance of cancer-associated sialyl-Tn antigen: Modulation of malignant phenotype in gastric carcinoma cells. Cancer Lett. 2006 Sep 9;[Epub ahead of print]: PMID: 16965854 |
86 | Chen L, Sundbäck J, Olofsson S, Jondal M. Interference with O-glycosylation in RMA lymphoma cells leads to a reduced in vivo growth of the tumor. Int J Cancer. 2006 Sep 15;119(6):1495-500 PMID: 16615117 |
77 | Croce MV, Isla-Larrain M, Rabassa ME, Demichelis S, Colussi AG, Crespo M, Lacunza E, Segal-Eiras A. Lewis x is highly expressed in normal tissues: a comparative immunohistochemical study and literature revision. Pathol Oncol Res. 2007 ;13(2):130-8 PMID: 17607374 |
57 | Tian E, Ten Hagen KG. O-linked glycan expression during Drosophila development. Glycobiology. 2007 Aug ;17(8):820-7 PMID: 17522109 |
93 | Saeland E, van Vliet SJ, Bäckström M, van den Berg VC, Geijtenbeek TB, Meijer GA, van Kooyk Y. The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma. Cancer Immunol Immunother. 2007 Aug ;56(8):1225-36 PMID: 17195076 |
94 | van Vliet SJ, Aarnoudse CA, Broks-van den Berg VC, Boks M, Geijtenbeek TB, van Kooyk Y. MGL-mediated internalization and antigen presentation by dendritic cells: a role for tyrosine-5. Eur J Immunol. 2007 Aug ;37(8):2075-81 PMID: 17616966 |
63 | de Faria PC Jr, Andreollo NA, Trevisan MA, Lopes LR. [Relationship of the sialomucins (Tn and Stn antigens) with adenocarcinoma in Barrett's esophagus] Rev Assoc Med Bras. 2007 Jul ;53(4):360-4 PMID: 17823742 |
64 | Norberg P, Olofsson S, Tarp MA, Clausen H, Bergström T, Liljeqvist JA. Glycoprotein I of herpes simplex virus type 1 contains a unique polymorphic tandem-repeated mucin region. J Gen Virol. 2007 Jun ;88(Pt 6):1683-8 PMID: 17485527 |
60 | Rajpert-De Meyts E, Poll SN, Goukasian I, Jeanneau C, Herlihy AS, Bennett EP, Skakkebaek NE, Clausen H, Giwercman A, Mandel U. Changes in the profile of simple mucin-type O-glycans and polypeptide GalNAc-transferases in human testis and testicular neoplasms are associated with germ cell maturation and tumour differentiation. Virchows Arch. 2007 Oct ;451(4):805-14 PMID: 17694322 |
83 | Lescar J, Sanchez JF, Audfray A, Coll JL, Breton C, Mitchell EP, Imberty A. Structural basis for recognition of breast and colon cancer epitopes Tn antigen and Forssman disaccharide by Helix pomatia lectin. Glycobiology. 2007 Oct ;17(10):1077-83 PMID: 17652409 |
79 | Wearne KA, Winter HC, Goldstein IJ. Temporal changes in the carbohydrates expressed on BG01 human embryonic stem cells during differentiation as embryoid bodies. Glycoconj J. 2008 Feb ;25(2):121-36 PMID: 17674202 |
70 | Toda M, Akita K, Inoue M, Taketani S, Nakada H. Down-modulation of B cell signal transduction by ligation of mucins to CD22. Biochem Biophys Res Commun. 2008 Jul 18;372(1):45-50 PMID: 18474217 |
62 | Medeiros A, Chiribao ML, Ubillos L, Festari MF, Saldaña J, Robello C, Domínguez L, Calvete JJ, Osinaga E. Mucin-type O-glycosylation in Mesocestoides vogae (syn. corti). Int J Parasitol. 2008 Mar ;38(3-4):265-76 PMID: 17892882 |
82 | Singha B, Adhya M, Chatterjee BP. Catfish (Clarias batrachus) serum lectin recognizes polyvalent Tn [alpha-D-GalpNAc1-Ser/Thr], Talpha [beta-D-Galp-(1-->3)-alpha-D-GalpNAc1-Ser/Thr], and II [beta-D-Galp(1-->4)-beta-D-GlcpNAc1-] mammalian glycotopes. Carbohydr Res. 2008 Sep 22;343(14):2384-92 PMID: 18662810 |
100 | Maveyraud L, Niwa H, Guillet V, Svergun DI, Konarev PV, Palmer RA, Peumans WJ, Rougé P, Van Damme EJ, Reynolds CD, Mourey L. Structural basis for sugar recognition, including the Tn carcinoma antigen, by the lectin SNA-II from Sambucus nigra. Proteins. 2009 Apr ;75(1):89-103 PMID: 18798567 |
98 | Kaszowska M, Norgren AS, Arvidson PI, Sandström C. Studies on the interactions between glycosylated beta3-peptides and the lectin Vicia villosa by saturation transfer difference NMR spectroscopy. Carbohydr Res. 2009 Dec 14;344(18):2577-80 PMID: 19863951 |
88 | Morita N, Yajima Y, Asanuma H, Nakada H, Fujita-Yamaguchi Y. Inhibition of cancer cell growth by anti-Tn monoclonal antibody MLS128. Biosci Trends. 2009 Feb ;3(1):32-7 PMID: 20103942 |
58 | Toda M, Hisano R, Yurugi H, Akita K, Maruyama K, Inoue M, Adachi T, Tsubata T, Nakada H. Ligation of tumour-produced mucins to CD22 dramatically impairs splenic marginal zone B-cells. Biochem J. 2009 Feb 1;417(3):673-83 PMID: 18925876 |
67 | Nowak M, Madej J, Dziegiel P, Lopuszynski W, Rodo A, Ugorski M. Tumor-associated carbohydrate antigens: Sialyl Lea and T/Tn antigens in canine mammary tumors. Vet Pathol. 2009 Mar ;46(2):222-6 PMID: 19261632 |
78 | Singh SK, Streng-Ouwehand I, Litjens M, Weelij DR, García-Vallejo JJ, van Vliet SJ, Saeland E, van Kooyk Y. Characterization of murine MGL1 and MGL2 C-type lectins: distinct glycan specificities and tumor binding properties. Mol Immunol. 2009 Mar ;46(6):1240-9 PMID: 19162326 |
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104 | Welinder C, Baldetorp B, Borrebaeck C, Fredlund BM, Jansson B. A new murine IgG1 anti-Tn monoclonal antibody with in vivo anti-tumor activity. Glycobiology. 2011 Aug ;21:1097-107 PMID: 21470982 |
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