3'-Sulfo Lewis a

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

Epitope information of EP0009

Epitope IDEP0009
Epitope name3'-Sulfo Lewis a
Structure
SequenceHSO3(-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-)-R
Aliases3'-Sulfo Lea
HistoryIn the early 1990's, it was reported that the 3'-sulphated Lea/Lex type tetrasaccharides were bound to selectins.[11][12*]
DB
Molecular weight609.6
Composition(Fuc)1(Gal)1(GlcNAc)1(HSO3)1
Species

Homo sapiens
Rattus norvegicus

Tissue and Cellular distribution

colon
esophagus
Gl. palatinales
Gl. sublinguales
Gl. submandibulares
prostate
salivary gland
skin
small intestine[4]
stomach
thymus

Subcellular distribution

Developmental change

Cell line

Receptor

3'-Sulfo Lea reportedly serves as a ligand for selectins.[11][12*]

Function

SO3-3-Gal and the SO3-3-Lea blood group antigen bound to H.pylori.[1]

Diseases

Application
Comment