AH6 / AH-6 / BM-1
| Antibody ID | AN0260 |
|---|
| Epitope ID | EP0018 |
|---|---|
| Epitope name | Lewis y |
| Recognition region | Fuc(a1-2)Gal(b1-4)[Fuc(a1-3)]GlcNAc-R |
| Immunoprecipitation | |
| Immunoblot | [1][4*][5][6] |
| ELISA/RIA | [4*] |
| Flow cytometry | [3] |
| Histochemistry | [1][2][6] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgM |
| Immunogen | MKN74/human gastric carcinoma[7*] |
| Availability | |
| Applications |
| 1 | Zhu ZM, Kojima N, Stroud MR, Hakomori S, Fenderson BA. Monoclonal antibody directed to Le(y) oligosaccharide inhibits implantation in the mouse. Biol Reprod. 1995 Apr ;52(4):903-12 PMID: 7780013 |
|---|---|
| 2 | Dohi T, Abe K, Ohshiba S. Immunohistochemical study of carbohydrate antigen expression in gastric carcinoma. Gastroenterol Jpn. 1989 Jun ;24(3):239-45 PMID: 2663606 |
| 3 | Muroi K, Suda T, Nojiri H, Ema H, Amemiya Y, Miura Y, Nakauchi H, Singhal A, Hakomori S. Reactivity profiles of leukemic myeloblasts with monoclonal antibodies directed to sialosyl-Le(x) and other lacto-series type 2 chain antigens:absence of reactivity with normal hematopoietic progenitor cells. Blood. 1992 Feb 1;79(3):713-9 PMID: 1370643 |
| 4 | Abe K, McKibbin JM, Hakomori S. The monoclonal antibody directed to difucosylated type 2 chain (Fuc alpha 1 leads to 2Gal beta 1 leads to 4[Fuc alpha 1 leads to 3]GlcNAc; Y Determinant). J Biol Chem. 1983 Oct 10;258(19):11793-7 PMID: 6194156 |
| 5 | Dohi T, Abe K, Ohshiba S, Yamaguchi K, Oshima M. Immunohistological and biochemical detection of fucosylated polylactosamine antigen with monoclonal antibody ACFH18 in gastric cancer and normal gastric mucosa. Jpn J Cancer Res. 1990 Jun ;81(6-7):676-81 PMID: 2119368 |
| 6 | Holmes EH, Ostrander GK, Clausen H, Graem N. Oncofetal expression of Lex carbohydrate antigens in human colonic adenocarcinomas. Regulation through type 2 core chain synthesis rather than fucosylation. J Biol Chem. 1987 Aug 15;262(23):11331-8 PMID: 3112156 |
| 7 | Farthmann EH, Fritsch WP. [Conditions after total gastrectomy]. Z Gastroenterol Verh. 1982 Apr ;17:17-23 PMID: 6191456 |