AH6 / AH-6 / BM-1

Antibody IDAN0260
Epitope ID EP0018
Epitope nameLewis y
Recognition regionFuc(a1-2)Gal(b1-4)[Fuc(a1-3)]GlcNAc-R
Flow cytometry[3]
ImmunogenMKN74/human gastric carcinoma[7*]
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1 Zhu ZM, Kojima N, Stroud MR, Hakomori S, Fenderson BA.
Monoclonal antibody directed to Le(y) oligosaccharide inhibits implantation in the mouse.
Biol Reprod. 1995 Apr ;52(4):903-12
PMID: 7780013
3 Muroi K, Suda T, Nojiri H, Ema H, Amemiya Y, Miura Y, Nakauchi H, Singhal A, Hakomori S.
Reactivity profiles of leukemic myeloblasts with monoclonal antibodies directed to sialosyl-Le(x) and other lacto-series type 2 chain antigens:absence of reactivity with normal hematopoietic progenitor cells.
Blood. 1992 Feb 1;79(3):713-9
PMID: 1370643
5 Dohi T, Abe K, Ohshiba S, Yamaguchi K, Oshima M.
Immunohistological and biochemical detection of fucosylated polylactosamine antigen with monoclonal antibody ACFH18 in gastric cancer and normal gastric mucosa.
Jpn J Cancer Res. 1990 Jun ;81(6-7):676-81
PMID: 2119368
2 Dohi T, Abe K, Ohshiba S.
Immunohistochemical study of carbohydrate antigen expression in gastric carcinoma.
Gastroenterol Jpn. 1989 Jun ;24(3):239-45
PMID: 2663606
6 Holmes EH, Ostrander GK, Clausen H, Graem N.
Oncofetal expression of Lex carbohydrate antigens in human colonic adenocarcinomas. Regulation through type 2 core chain synthesis rather than fucosylation.
J Biol Chem. 1987 Aug 15;262(23):11331-8
PMID: 3112156
4 Abe K, McKibbin JM, Hakomori S.
The monoclonal antibody directed to difucosylated type 2 chain (Fuc alpha 1 leads to 2Gal beta 1 leads to 4[Fuc alpha 1 leads to 3]GlcNAc; Y Determinant).
J Biol Chem. 1983 Oct 10;258(19):11793-7
PMID: 6194156
7 Farthmann EH, Fritsch WP.
[Conditions after total gastrectomy].
Z Gastroenterol Verh. 1982 Apr ;17:17-23
PMID: 6191456