HBTn1 / HB-Tn1

Antibody IDAN0366
Epitope ID EP0021
Epitope nameTn Antigen
Recognition regionGalNAc(a1-)Ser/Thr
Flow cytometry[5][9]
Up  Down
3 Wong ET, Lindall AW.
Subcellular location of human parathyroid hormone immunoreactive peptides and preliminary evidence for a precursor to human PTH-1 (38545).
Proc Soc Exp Biol Med. 1975 Feb ;148(2):387-92
PMID: 1121486
1 Terasawa K, Furumoto H, Kamada M, Aono T.
Expression of Tn and sialyl-Tn antigens in the neoplastic transformation of uterine cervical epithelial cells.
Cancer Res. 1996 May 1;56(9):2229-32
PMID: 8616877
4 Giuffre G, Vitarelli E, Tuccari G, Barresi G.
Immunohistochemical study of Tn, sialosyl-Tn and T antigens in human meningiomas.
Eur J Histochem. 1998 ;42(3):197-203
PMID: 9857245
2 Takano Y, Teranishi Y, Terashima S, Motoki R, Kawaguchi T.
Lymph node metastasis-related carbohydrate epitopes of gastric cancer with submucosal invasion.
Surg Today. 2000 ;30(12):1073-82
PMID: 11193738
11 Julien S, Krzewinski-Recchi MA, Harduin-Lepers A, Gouyer V, Huet G, Le Bourhis X, Delannoy P.
Expression of sialyl-Tn antigen in breast cancer cells transfected with the human CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase (ST6GalNac I) cDNA.
Glycoconj J. 2001 Nov ;18(11-12):883-93
PMID: 12820722
10 Sakuraba H, Matsuzawa F, Aikawa S, Doi H, Kotani M, Nakada H, Fukushige T, Kanzaki T.
Structural and immunocytochemical studies on alpha-N-acetylgalactosaminidase deficiency (Schindler/Kanzaki disease).
J Hum Genet. 2004 ;49(1):1-8
PMID: 14685826
9 Sotiriadis J, Shin SC, Yim D, Sieber D, Kim YB.
Thomsen-Friedenreich (T) antigen expression increases sensitivity of natural killer cell lysis of cancer cells.
Int J Cancer. 2004 Sep 1;111(3):388-97
PMID: 15221966
5 Ragupathi G, Liu NX, Musselli C, Powell S, Lloyd K, Livingston PO.
Antibodies against tumor cell glycolipids and proteins, but not mucins, mediate complement-dependent cytotoxicity.
J Immunol. 2005 May 1;174(9):5706-12
PMID: 15843572
7 Yano H, Yamamoto-Hino M, Abe M, Kuwahara R, Haraguchi S, Kusaka I, Awano W, Kinoshita-Toyoda A, Toyoda H, Goto S.
Distinct functional units of the Golgi complex in Drosophila cells.
Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13467-72
PMID: 16174741
6 Kawaguchi T, Takazawa H, Imai S, Morimoto J, Watanabe T, Kanno M, Igarashi S.
Expression of Vicia villosa agglutinin (VVA)-binding glycoprotein in primary breast cancer cells in relation to lymphatic metastasis: is atypical MUC1 bearing Tn antigen a receptor of VVA?
Breast Cancer Res Treat. 2006 Jul ;98(1):31-43
PMID: 16752227
8 Croce MV, Isla-Larrain M, Rabassa ME, Demichelis S, Colussi AG, Crespo M, Lacunza E, Segal-Eiras A.
Lewis x is highly expressed in normal tissues: a comparative immunohistochemical study and literature revision.
Pathol Oncol Res. 2007 ;13(2):130-8
PMID: 17607374