SSEA-3

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

Epitope information of EP0039

Epitope IDEP0039
Epitope nameSSEA-3
Structure
SequenceGal(b1-3)GalNAc(b1-3)Gal(a1-)-R
Aliasesstage specific embryonic antigen-3
HistoryIt was proposed that cell surface plays an important role during embryogenesis. Each blastomere of the 8-cell-stage mouse embryo appeares to have the genetic potential to develop into a complete organism.
DB GlyTouCan:G25129BT JCGGDB
Molecular weight545.5
Composition(Gal)2(GalNAc)1
Species

Homo sapiens
Mus musculus
Rattus norvegicus
Tissue and Cellular distribution

cancer/embryonal carcinoma [1]
cancer/teratocarcinoma(human)[2]
cancer/yolk sac carcinoma[1]
cancer cell lines[4]
early cleavage stage embyonic cell[1]
embryonic cell[1]
erythrocyte(human)[2]
fertilized egg[1]
follicular ova[1]
ovarian oocyte[2]
zygote (mouse embryo)[2]
testis[1]
visceral endodermal cell[1]
Subcellular distribution
Developmental change

SSEA-3 was detected by a monoclonal antibody raised 4- to 8-cell stage mouse embryos.[2]
Cell line

2102E/teratocarcinoma[3]
734-B/human breast carcinoma[4]
833-K/teratocarcinoma[3]
AlAb/human breast carcinoma[4]
BT-20/human breast carcinoma[4]
MCF-7/human breast adenocarcinoma[4]
MDA-MB-231/human breast carcinoma[4]
SK-LC-13/human lung carcinoma[4]
SK-LY-16/human leukemia[4]
SK-OV-6/human ovarian carcinoma[4]
SK-RC-1/human renal cell carcinoma[4]
SK-RC-29/human renal cell carcinoma[4]
SK-RC-39/human renal cell carcinoma[4]
SK-RC-49/human renal cell carcinoma[4]
SK-RC-7/human renal cell carcinoma[4]
SK-UT-1/human uterine leiomyosarcoma[4]
Receptor
Function
Diseases

embryonal carcinoma[1]
teratocarcinoma[2]
yolk sac carcinoma[1]
Application
Comment