91.9H
| Antibody ID | AN0169 |
|---|
| Epitope ID | EP0009 |
|---|---|
| Epitope name | 3'-Sulfo Lewis a |
| Recognition region | HSO3(-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal-R |
| Immunoprecipitation | |
| Immunoblot | [2][1] |
| ELISA/RIA | |
| Flow cytometry | |
| Histochemistry | [3][4*][5] |
| Comment |
| Species | Mouse |
|---|---|
| Category | Monoclonal |
| Isotype | IgG1 |
| Immunogen | sulfomucin from human colonie mucosa[6] |
| Availability | |
| Applications |
| 1 | Tsuiji H, Nakatsugawa S, Ishigaki T, Irimura T. Malignant and other properties of human colon carcinoma cells after suppression of sulfomucin production in vitro. Clin Exp Metastasis. 1999 Mar ;17(2):97-104 PMID: 10411100 |
|---|---|
| 2 | Loveless RW, Yuen CT, Tsuiji H, Irimura T, Feizi T. Monoclonal antibody 91.9H raised against sulfated mucins is specific for the 3'-sulfated Lewisa tetrasaccharide sequence. Glycobiology. 1998 Dec ;8(12):1237-42 PMID: 9858646 |
| 3 | Tsuiji H, Hong JC, Kim YS, Ikehara Y, Narimatsu H, Irimura T. Novel carbohydrate specificity of monoclonal antibody 91.9H prepared against human colonic sulfomucin: recognition of sulfo-Lewis(a) structure. Biochem Biophys Res Commun. 1998 Dec 18;253(2):374-81 PMID: 9878545 |
| 4 | Ikeda N, Eguchi H, Nishihara S, Narimatsu H, Kannagi R, Irimura T, Ohta M, Matsuda H, Taniguchi N, Honke K. A remodeling system of the 3'-sulfo-Lewis a and 3'-sulfo-Lewis x epitopes. J Biol Chem. 2001 Oct 19;276(42):38588-94 PMID: 11504739 |
| 5 | Bodger K, Campbell F, Rhodes JM. Detection of sulfated glycoproteins in intestinal metaplasia: a comparison of traditional mucin staining with immunohistochemistry for the sulfo-Lewis(a) carbohydrate epitope. J Clin Pathol. 2003 Sep ;56(9):703-8 PMID: 12944557 |
| 6 | Yamori T, Ota DM, Cleary KR, Hoff S, Hager LG, Irimura T. Monoclonal antibody against human colonic sulfomucin: immunochemical detection of its binding sites in colonic mucosa, colorectal primary carcinoma, and metastases. Cancer Res. 1989 Feb 15;49(4):887-94 PMID: 2912559 |