Chondroitin

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

3 biosynthetic enzyme for EP0081

NameChSy-1(CSS1)
ReactionGalNAc(b1-4)GlcA + UDP-GlcA = GlcA(b1-3)GalNAc(b1-4)GlcA + UDP (EC 2.4.1.226)
GlcA(b1-3)GalNAc + UDP-GalNAc = GalNAc(b1-4)GlcA(b1-3)GalNAc + UDP (EC 2.4.1.175)
DescriptionChondroitin synthase-1 / Chondroitin sulfate synthase-1
ECEC 2.4.1.226
DBNCBI/Gene Swissprot/TrEMBL
Gene deficient organisms[9][10]
Comment
NameChSy-2(CSS3)
ReactionGalNAc(b1-4)GlcA + UDP-GlcA = GlcA(b1-3)GalNAc(b1-4)GlcA + UDP (EC 2.4.1.226)
GlcA(b1-3)GalNAc + UDP-GalNAc = GalNAc(b1-4)GlcA(b1-3)GalNAc + UDP (EC 2.4.1.175)
DescriptionChondroitin synthase-2 / Chondroitin sulfate synthase-3
ECEC 2.4.1.226
DBNCBI/Gene Swissprot/TrEMBL
Gene deficient organisms
Comment
NameChSy-3(CSGlcAT)
ReactionGalNAc(b1-4)GlcA + UDP-GlcA = GlcA(b1-3)GalNAc(b1-4)GlcA + UDP (EC 2.4.1.226)
GlcA(b1-3)GalNAc + UDP-GalNAc = GalNAc(b1-4)GlcA(b1-3)GalNAc + UDP (EC 2.4.1.175)
DescriptionChondroitin synthase-3 / Chondroitin sulfate glucuronyltransferase
ECEC 2.4.1.226
DBNCBI/Gene Swissprot/TrEMBL
Gene deficient organisms
Comment

0 degradation enzyme for EP0081