Sialyl Lewis a

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

3 biosynthetic enzyme for EP0008

NameReaction
ST3Gal III,ST3Gal IV Gal(b1-3)GlcNAc(b1-)-R + CMP-Neu5Ac = Neu5Ac(a2-3)Gal(b1-3)GlcNAc(b1-)-R + CMP
FUT3 Neu5Ac(a2-3)Gal(b1-3)GlcNAc-R + GDP-Fuc = Neu5Ac(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc-R + GDP
NameST3Gal III
ReactionGal(b1-3)GlcNAc(b1-)-R + CMP-Neu5Ac = Neu5Ac(a2-3)Gal(b1-3)GlcNAc(b1-)-R + CMP
Descriptionalpha-2,3-sialyltransferase ST3Gal III / SiaT6
ECEC 2.4.99.6
DBNCBI/Gene Swissprot/TrEMBL CAZy:GT29
Gene deficient organisms
Comment
NameST3Gal IV
ReactionGal(b1-3)GlcNAc(b1-)-R + CMP-Neu5Ac = Neu5Ac(a2-3)Gal(b1-3)GlcNAc(b1-)-R + CMP
Descriptionalpha-2,3-sialyltransferase ST3Gal IV / SiaT4c
ECEC 2.4.99.-
DBNCBI/Gene Swissprot/TrEMBL CAZy:GT29
Gene deficient organisms
Comment
NameFUT3
ReactionNeu5Ac(a2-3)Gal(b1-3)GlcNAc-R + GDP-Fuc = Neu5Ac(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc-R + GDP
Descriptionalpha1-3/4FUT / Galactoside 3(4)-L-fucosyltransferase / Blood group Lewis alpha-4-fucosyltransferase / Lewis FT / Fucosyltransferase 3
ECEC 2.4.1.65
DBNCBI/Gene Swissprot/TrEMBL CAZy:GT10
Gene deficient organisms
Comment

0 degradation enzyme for EP0008