GQ1b alpha

General | Antibody | Glycoprotein | Glycolipid | Enzyme | Reference

Epitope information of EP0112

Epitope IDEP0112
Epitope nameGQ1b alpha
Structure
SequenceNeu5Ac(a2-3)Gal(b1-3)[Neu5Ac(a2-6)]GalNAc(b1-4)[Neu5Ac(a2-8)Neu5Ac(a2-3)]Gal(b1-4)Glc(b1-1)Cer
AliasesChol-1 alpha-b
HistoryA new ganglioside antigen, termed Chol-1 alpha-b, recognized by cholinergic neuron-specific antibody,Chol-1 alpha, was isolated from bovine brain ganglioside mixture using Q-Sepharose. This ganglioside was determinated IV3NeuAc,III6NeuAc,II3NeuAc2GgOse4Cer.[4]
DB GlyTouCan:G54733XO JCGGDB
Molecular weight1872.7(Cer)
Composition(Gal)2(GalNAc)1(Glc)1(Neu5Ac)4(Cer)1
Species

Bos taurus[4*]
Rattus norvegicus[3]
Tissue and Cellular distribution

brain(bovine)[4*]
central nervous system(rat)[3]
Subcellular distribution
Developmental change
Cell line
Receptor
Function

GQ1b alpha was a cholinergic specific antigen.
Diseases
Application
Comment